Senior Manager - Single Cell Biology

The Senior Manager of Single Cell Biology leads the operational execution of multi‑platform laboratory services, overseeing managers and technical staff to ensure high‑quality, efficient support for complex research projects. This role translates strategic priorities into actionable operational plans, coordinating personnel, resources, and timelines while developing comprehensive training and professional development programs for staff at all levels. Acting as a key liaison across teams and stakeholders, the Senior Manager drives effective communication, collaboration, and project execution, while also managing budgets, inventory, and resource planning. Through strong leadership and continuous improvement of workflows, this role advances the laboratory's scientific capabilities and ensures alignment between staff development, project delivery, and broader organizational objectives. Key Responsibilities Lead, mentor, and develop a multidisciplinary team of scientists and research associates; build organizational capabilities and succession pipelines. Oversee design, optimization, and execution of single‑cell, spatial, and high‑content biology workflows to support discovery and translational programs. Drive strategic planning for platform expansion, technology evaluation, and process scalability. Own tactical coordination for multi-assay or large-scale projects, working in partnership with Senior Leadership and other areas of the organization. Manage complex project portfolios, resource allocation, timelines, and cross‑functional communication. Ensure operational excellence through robust SOPs, quality systems, safety compliance, and laboratory best practices. Identify and implement operational improvements to laboratory workflows, throughput, and quality Present scientific insights and platform updates to senior leadership and contribute to program‑level decision‑making. Knowledge, Skills, and Abilities Proven leadership managing multi‑level scientific staff (technicians through managers) with a strong track record in structured training, mentorship, and performance management. Advanced operational planning skills across diverse assay platforms and lab sites, including autonomous oversight of budgets, inventory, and resource allocation. Ability to translate strategic scientific direction into coordinated, cross‑platform operational execution; broad understanding of core laboratory competencies and adjacent scientific services. Deep expertise in RNA biology, single‑cell profiling platforms, and spatial transcriptomic/proteomic assays, supported by 10+ years of experience in molecular and single‑cell biology within biotech or pharmaceutical R D. Demonstrated ability to make independent, high‑impact decisions under tight timelines, with strong troubleshooting, communication, and interpersonal skills for navigating complex stakeholder environments. Experience handling and interpreting complex biological data, ensuring scientific rigor while maintaining a proactive, organized, and flexible leadership approach.

Education:

Master's Degree required/ PhD preferred

Experience:

4 years required/ 6 years preferred

Supervisory:

4 years required/ 6 years preferred

Pay Range:

$98885 - $165554

About JAX:

The Jackson Laboratory is an independent, nonprofit biomedical research institution with a National Cancer Institute-designated Cancer Center and nearly 3,000 employees in locations across the United States (Maine, Connecticut, California), Japan and China. Its mission is to discover precise genomic solutions for disease and empower the global biomedical community in the shared quest to improve human health. Founded in 1929, JAX applies over nine decades of expertise in genetics to increase understanding of human disease, advancing treatments and cures for cancer, neurological and immune disorders, diabetes, aging and heart disease. It models and interprets genomic complexity, integrates basic research with clinical application, educates current and future scientists, and provides critical data, tools and services to the global biomedical community. For more information, please visit www.jax.org.

EEO Statement:

The Jackson Laboratory provides equal employment opportunities to all employees and applicants for employment in all job classifications without regard to race, color, religion, age, mental disability, physical disability, medical condition, gender, sexual orientation, genetic information, ancestry, marital status, national origin, veteran status, and other classifications protected by applicable state and local non-discrimination laws.

Bar Harbor:

The Jackson Laboratory's 43-acre scenic Bar Harbor campus is nestled between the Gulf of Maine and the mountains of Acadia National Park. Some of the best hiking and biking in the world (over 50 square miles of mountains, lakes, views, and dramatic coastline) is accessible from our campus. We are one mile from downtown Bar Harbor, which offers a vibrant downtown district with a plethora of restaurants, shops, museums, and galleries.

Ellsworth:

The Charles E. Hewett Center in Ellsworth, Maine, is a state-of-the-art facility that serves researchers world wide. The facility represents the culmination of nine decades of unmatched experience and leadership in breeding and caring for laboratory mice. Ellsworth, Maine, is one of Maine's fastest growing cities. With a growth rate of nearly 20%, Ellsworth is a bustling year-round community and acts as a hub for surrounding towns. It is located nearby Acadia National Park and hosts numerous special events, concerts and festivals each year. Residents have access to fabulous shopping, recreation, museums, galleries, and dining at a variety of independent restaurants.

Farmington:

JAX Genomic Medicine is transforming medicine by improving patient care, lowering costs, and increasing life span and health span. JAX Genomic Medicine's research focuses on the complex genetic causes of disease and on the development of genomic solutions tailored to each person's unique genetic makeup. JAX Genomic Medicine sits on a 17-acre site on the campus of the University of Connecticut Health Center. The 183,500-square-foot facility opened in the fall of 2014. Now, it houses over 300 biomedical researchers, technicians, and support staff in state-of-the-art computing facilities and laboratories. In Connecticut, JAX resides in the scenic town of Farmington, in the state's capitol region. The Hartford region, which offers some of the best public schools in the country, is made up of both bigger cities and smaller, charming historic New England towns. JAX Genomic Medicine is also geographically located within 2 hours of Boston and New York and is close to multiple transportation systems, including bus lines, highways, railroads and international airports.

Sacramento:

The JAX® Mice, Clinical and Research Services facility is located in Sacramento, the state capital of California. Sacramento is less than a two-hour drive from San Francisco, Napa Valley, and scenic Lake Tahoe, and a short flight to both Los Angeles and Orange County. Sacramento is the birthplace of the nation's Farm to Fork movement, and offers excellent restaurants, gastro-pubs, wineries, theaters, and museums.

Outdoor activities are plentiful:

Boating, white water rafting, and riding the scenic bicycle trails are popular. Housing and other costs of living are more affordable in Sacramento and its surrounding suburbs than in most other neighboring areas in the North Bay, making Sacramento one of the hottest housing markets in the country year after year.

Augusta:

JAX's Maine Cancer Genomics Initiative (MCGI) is located in Augusta, Maine, in the Harold Alfond Center for Cancer Care (HACCC), at Maine General Hospital. It began operations in 2016 with three overarching goals: to provide cancer genomic testing for Maine cancer patients; to develop and deliver physician education about clinical genomic cancer diagnostics; and to build a network in Maine of oncology practices conducting studies in genomic medicine.