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Research Fellow-Translational Neuroproteomics-Rossoll lab
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Mayo Foundation for Medical Education and Research
Jacksonville, FL (In Person)
Full-Time
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Job Description
The Translational Neuroproteomics Laboratory (Rossoll Lab) is seeking a highly motivated Postdoctoral Research Fellow to join our Foundation-funded project to define the proteomic composition and molecular environment of pathological phospho-TDP-43 (pTDP-43) aggregates in human brain tissue and determine how these associated proteins contribute to neurodegeneration in sporadic frontotemporal lobar degeneration (FTLD-TDP). The project integrates microscope-guided photolabeling/proximity proteomics in FFPE human brain tissue, affinity purification, data-independent acquisition LC-MS/MS, multiplexed spatial biology, proteomics data analysis, and functional validation in cellular and organotypic brain-slice culture models of TDP-43 proteinopathy. The position offers an opportunity to work in a highly interactive neuroscience community at Mayo Clinic Florida, with access to world-class facilities, including the Multiomics Mass Spectrometry (MMS) core, and the Mayo Clinic brain bank. Interested applicants should send a cover letter, CV, and contact information for three references to Dr. Wilfried Rossoll at rossoll.wilfried@mayo.edu.
Location:
Jacksonville, Florida Contact:
Dr. Wilfried Rossoll — rossoll.wilfried@mayo.edu More info:
https://www.mayo.edu/research/labs/rossoll-lab A Research Fellow at Mayo Clinic is a temporary position intended to provide training and education in research. Individuals will train in the research program of a Mayo Clinic principal investigator. Qualified individuals will demonstrate the potential for research as evidenced by their training and peer-reviewed publications and should become competitive for national research grants. Proof of English proficiency is required for J-1 Short-Term Scholars, Research Scholars, Professors, Specialists, and Student Interns sponsored by Mayo Clinic.- Ph.D. (or equivalent) in Neuroscience, Cell or Molecular Biology, Biochemistry, or related field
- Strong background in molecular and cell biology techniques, biochemistry, and fluorescence microscopy
- Experience with tissue, cell culture, and proteomics is desirable
- Excellent organizational, communication, and teamwork skills