IVB-Stem Cell Biology and Embryology

The IVB Scientist will play a key role in advancing innovative approaches in cattle reproductive biology within our Innovation group. This position requires deep expertise in stem cell culture and embryology, supported by a strong foundation in developmental biology or regenerative medicine. The Scientist will lead experimental design, troubleshooting, and protocol development to drive stem cell-based advancements that directly enable next generation commercial breeding applications. This position reports to the Chief Scientific Officer, Recombinetics (URUS Innovation Group) and will be based in Minneapolis/St. Paul metropolitan area (onsite collaboration required) .

RESPONSIBILITIES

Stem Cell Line Development and Optimization Optimize, generate, and culture stem cell lines from various sources. Implement innovations to enhance quality control, consistency, and scalability of stem cell workflows. Experimental Design, Troubleshooting, and Method Development Lead experimental design and execute studies to improve stem cell cloning applications. Troubleshoot technical challenges and develop/refine protocols to improve reproducibility and outcomes. Differentiation and Organoid Modeling Develop and optimize protocols for cattle stem cell differentiation. Establish and maintain organoid models for experimental and developmental biology applications. Data Analysis and Interpretation Analyze and interpret complex datasets, including sequencing and multiomics data. Summarize findings and communicate progress to internal teams with clarity and scientific rigor. Cross-Functional Collaboration Partner with genomics, data science, and reproductive biology teams to prioritize work streams and align project timelines. Contribute to interdisciplinary planning and decision-making. Documentation and Quality Management Maintain meticulous experimental records, lab notebooks, and data logs. Develop and maintain SOPs, tracking systems, and documentation frameworks to ensure reliability and transferability of protocols. Continuous Learning and Innovation Stay current with advances in embryology, stem cell technologies, and organoid culture. Integrate emerging methods and technologies into ongoing workflows where appropriate.

PROFESSIONAL QUALIFICATIONS AND EXPERIENCES

Ph.D. in Developmental Biology, Reproductive Biology, Stem Cell Biology, or a related field, or equivalent work experience. Strong scientific foundation and a track record of executing complex experiments with rigor. Proven expertise in stem cells, organoid cultures and/or stem cell differentiation. Experience in developmental biology or regenerative medicine is a plus. Strong understanding of reproductive and molecular biology. Experience with bioinformatics tools, databases, and analysis methods for genomic/proteomic data. Knowledge in probability, statistical modeling, and algorithm design. Experience with generation or analysis of large-scale OMIC datasets (e.g., bulk transcriptomics, epigenetics and single-cell multi-omics. Experience with immunofluorescence analysis, FACS sorting, microdissection, or micromanipulation is highly desirable. Analytical thinking to translate biological questions into computational problems (e.g., integrating multi-omics datasets to identify genotype-phenotype links). Demonstrated ability to independently design, execute, and interpret complex experiments. Strong troubleshooting skills and data driven decision making. Experience mentoring or leading others with high scientific rigor. Excellent communication skills for interdisciplinary teamwork and reporting. Team oriented mindset with willingness to support hands on lab work. Adaptable, proactive, and eager to learn new tools in a fast paced environment.