Postdoctoral fellow Employer Duke University Location Durham, North Carolina Salary Commensurate with experience and University pay scales Closing date Oct 10, 2026 View more categories View less categories Sector Graduate School or University Job Function Postdoctoral Researcher Position Type Full Time Level Any Experience Level Considered Apply now Save job Click to add the job to your shortlist You need to sign in or create an account to save a job. Send job Job Details Postdoctoral Associate Boyce Lab, Duke University School of Medicine The Boyce Laboratory in the Department of Biochemistry at Duke University seeks a talented, motivated, and collegial postdoctoral fellow to join a newly funded

NINDS R01

project investigating how O-GlcNAc glycosylation regulates KLHL-family E3 ubiquitin ligases (gigaxonin, KLHL3) and their substrates (neurofilaments, WNK kinases) in neuronal proteostasis, cytoskeletal dynamics, and ferroptotic cell death. This collaborative work combines neurobiology, biochemistry, chemical biology, cell signaling, live-cell imaging, and organotypic brain slice models to dissect the mechanistic links between intracellular glycosylation and neurodegeneration. By mutual agreement with the PI, the exact portfolio within the larger project may be adjusted to suit the postdoc's background, interests, and professional goals. We are looking for a candidate with a Ph.D. or equivalent doctoral training in neurobiology, cell biology, biochemistry, or a related field, who is intellectually curious, works well independently and as part of a team, and is committed to rigorous, reproducible science. Research experience in cellular neurobiology and/or O-GlcNAc signaling or glycobiology more broadly is strongly preferred but not strictly required. The successful candidate will have access to a rigorous, well-funded, inclusive, and highly collaborative research environment with state-of-the-art core facilities and opportunities to develop independent expertise across multiple experimental systems, from cell lines to primary neurons to ex vivo brain tissue. The postdoc will be encouraged to develop a unique scientific identity within the broader project, lead publications, present their work at national conferences, mentor junior researchers, and develop the skills and preliminary data needed for an independent research career in any sector. Scientists with strong backgrounds in adjacent areas and a firm commitment to learning glycobiology approaches are also encouraged to apply. Interested candidates should include a CV, brief statement of research interests, and contact information for three references in their applications. Duke is an Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex (including pregnancy and pregnancy related conditions), sexual orientation or military status. Duke aspires to create a community built on collaboration, innovation, creativity, and belonging. Our collective success depends on the robust exchange of ideas—an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of the community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard. All members of our community have a responsibility to uphold these values. Share this job Facebook Twitter LinkedIn Apply now