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UO
University of Minnesota
Research Assistant
Career Insights for Cell Biologist
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What they do
A Cell Biologist studies plant and animal life and conducts research to understand cells and cell systems. May teach cell biology or specialize in clinical research, cell culture, medical research and treatment, pharmaceutical, biotechnology or plant research. Directs research experiments and staff, operates specialized equipment and analyzes and reports research results.
$80,776 / year median in Minnesota
+9% projected growth
Job Description
About the Job The Graduate Assistant position is available in the Pulmonary Vascular Biology Laboratory to investigate the molecular and cellular mechanisms underlying pulmonary vascular remodeling and right ventricular adaptation in pulmonary hypertension reporting to Dr. Aleksandra Babicheva. The successful candidate will combine experimental physiology with computational biology and bioinformatics approaches to analyze multi-dimensional biological datasets and generate new mechanistic insights. This position is expected to work four hours a day Monday-Friday. This position is covered by the Graduate Labor Union-United Electrical, Radio and Machine Workers of America Local 1105. Appointments are offered each semester according to UMN academic calendars. The employer retains the right to change or assign other duties to this position as needed. The deadline to apply is September 4, 2026.
Duties & Responsibilities:
- Maintain mouse colonies (i.e., breeding and genotyping), managing lab research records (e.g., methodological approaches, experimental records, and protocols).
- Work with others in the lab to assist with the pharmacological experiments in rodents including sample collection to test the therapeutic potential of drugs to treat pulmonary hypertension and right heart failure.
- Conduct laboratory-based research using cellular and animal models of cardiopulmonary disease and performing molecular biology, cell biology, histology, microscopy, and physiological experiments.
- Design a method to isolate pulmonary vascular endothelial and smooth muscle cells from human and animal specimens.
- Processing and analyzing transcriptomic datasets (bulk RNA-seq and/or single-cell RNA-seq), performing differential gene expression, pathway enrichment, and gene ontology analyses, integrating publicly available genomic and transcriptomic datasets with laboratory-generated data, developing reproducible data analysis workflows using R and/or Python.
- Organizing supplies, materials or equipment and setting-up equipment for laboratory experiments or demonstrations; may perform minor equipment maintenance.
- Responsibilities will include data acquisition and analysis, grant and manuscript preparation, and presentation of findings during weekly lab meetings.
- Cleaning glassware and other laboratory equipment or materials using appropriate standards; keeping laboratory area clean.
Focus of Job Responsibilities:
70% - Ongoing Research- Design and implementation of hypothesis-driven research projects. 15% - Analysis & Review
- Analysis and review of generated data.
- Review of scientific literature. 15% - Scientific writing
- Preparation of manuscripts for publication in peer-reviewed journals.
- Preparation of grants proposals for submission to seek research funding.
- Bachelor's degree.
- Previous laboratory experience.
- Understanding of basic molecular techniques.
- Excellent written, oral communication and critical thinking skills.
- Excellent attention to detail and accuracy. Preferred Qualifications
- Experience with isolation of primary cells (human, rodent).
- Experience with electrophysiological experiments (patch-clamp).
- Ability to use software for statistics such as EXCEL, SigmaPlot, GraphPad, Prism, RedCap.
- Knowledge of research and laboratory equipment appropriate to the area of the assignment. Physical & Environmental Requirements
- Must be comfortable working in environments that may include close contact with animals, animal byproducts, and related materials.
- Exposure to varying temperatures, outdoor environments, and potential odors or airborne particles related to animal care.