Senior Scientist Medium Scale Oligo Synthesis

Senior Scientist Medium Scale Oligo Synthesis Merck KGaA

• 3.8 Billerica, MA Job Details $111,100
• $166,600 a year 1 day ago Benefits Health insurance Paid time off Opportunities for advancement Qualifications Doctor of Philosophy Full Job Description Work Your Magic with us! Start your next chapter and join EMD Serono. Ready to explore, break barriers, and discover more? We know you've got big plans
• so do we!

Our colleagues across the globe love innovating with science and technology to enrich people's lives with our solutions in Healthcare, Life Science, and Electronics. Together, we dream big and are passionate about caring for our rich mix of people, customers, patients, and planet. That's why we are always looking for curious minds that see themselves imagining the unimaginable with us. United As One for Patients, our purpose in Healthcare is to help create, improve and prolong lives. We develop medicines, intelligent devices and innovative technologies in therapeutic areas such as Oncology, Neurology and Fertility. Our teams work together across 6 continents with passion and relentless curiosity in order to help patients at every stage of life. Joining our Healthcare team is becoming part of a diverse, inclusive and flexible working culture, presenting great opportunities for personal development and career advancement across the globe. This role does not offer sponsorship for work authorization. External applicants must be eligible to work in the US.

Your Role:

Design, synthesis, purification and analysis of ASO. siRNA and/or its conjugates to small molecules, Peptides, Dyes and Antibodies. Ability to operate Mermade 12 and Akta Synth synthesizers using Phosphoramidite chemistry. Solid phase synthesis of oligonucleotides at medium scales (20 mg

• 1.

0 g), Large Scale Purification and Ultrafiltration of oligonucleotides by anion-exchange and reverse-phase HPLC systems, Deep understanding of oligonucleotide and precursor synthesis, purification, and familiarity with analytical methods in oligonucleotide drug development. Demonstrate an ability to work as part of a team and possess an excellent work ethic. Present funding in team meetings. Maintain a well-documented laboratory notebook and follow the safe laboratory practices. Multi-task across several projects and manage time effectively to achieve results.

Who You Are Minimum Qualifications:

PhD in Chemistry, science or engineering. 5+ years of direct experience in oligonucleotide chemistry.

Preferred Qualifications:

Strong knowledge of Oligonucleotide Synthesis, Deprotection and Purification techniques. Knowledge and background in bioconjugation chemistry including antibody-drug conjugates and related linkers. Experience in conjugation/bioconjugation chemistry. Solid-phase synthesis techniques with oligonucleotides or peptides. Expertise in chromatography purification techniques and troubleshooting. Strong laboratory skills and experience with analytical instrumentation such as NMR, HPLC, LC-MS, etc. with the ability to analyze, interpret, and clearly present data.

Pay Range for this position:

$111,100

• 166,600.

The offer range represents the anticipated low and high end of the base pay compensation for this position. The actual compensation offered will be determined by factors such as location, level of experience, education, skills, and other job-related factors. Position may be eligible for sales or performance-based bonuses. Benefits offered by the Company include health insurance, paid time off (PTO), retirement contributions, and other perquisites. For more information click here .

What we offer:

We are curious minds that come from a broad range of backgrounds, perspectives, and life experiences. We believe that this variety drives excellence and innovation, strengthening our ability to lead in science and technology. We are committed to creating access and opportunities for all to develop and grow at your own pace. Join us in building a culture of inclusion and belonging that impacts millions and empowers everyone to work their magic and champion human progress! Apply now and become a part of a team that is dedicated to Sparking Discovery and Elevating Humanity!