Senior Scientist, Bioscience

Job Title:

Senior Scientist, Bioscience Location:

Waltham, MA At AstraZeneca, we put patients first and strive to meet their unmet needs worldwide. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality. If you are swift to action, confident to lead, willing to collaborate, and curious about what science can do, then you're our kind of person. Recognizing the importance of individualized flexibility, our ways of working allow employees to balance personal and work commitments while ensuring we continue to create a strong culture of collaboration and teamwork by engaging face-to-face in our offices 3 days a week. Our head office is purposely designed with collaboration in mind, providing space where teams can come together to strategize, brainstorm and connect on key projects. Our dedication to sustainability is also central to our culture and part of what makes AstraZeneca a great place to work. We know the health of people, the planet and our business are interconnected which is why we're taking ambitious action to tackle some of the biggest challenges of our time, from climate change to access to healthcare and disease prevention. Introduction to

Role:

AstraZeneca is seeking a highly motivated Senior Scientist with a background in tumor immunology, T cell engagers, or a related field to join our dynamic team in Waltham, MA. This is an exciting opportunity to contribute to our mission of eliminating cancer as a cause of death. As a Senior Scientist, you will be a key player in supporting NeuroOncology and other rare cancers projects through the drug discovery process, using your expertise in immunology to establish assay systems and deliver datasets that will have direct impact on pipeline programs.

Accountabilities:

In this laboratory-based position within the Rare Cancer Discovery group, you will develop, conduct and analyze experiments to assess the function of our candidate drugs. You will design novel therapeutics targeting the immune system for brain tumors therapy and help to dissect their mechanism of action. You will support cross-functional teams and work collaboratively with colleagues to ensure the timely generation and dissemination of critical program data. Additionally, you will review emerging literature and internal data to help in identifying new potential targets and contribute to target validation activities.

Essential Skills/Experience:

A PhD in cancer biology, immunology and/or immuno-oncology, with at least 3 years of post-doctoral experience or appropriate industry experience, in a relevant research area. Strong background in tumor immunology and experience with performing standard in vitro assays (immune cell activation, cytotoxic assays, etc). Strong background in NeuroOncology and in vivo models Experience with multi-color flow cytometry to evaluate mouse and/or human T cell populations and functions. Ability to independently design and execute research plans for one or more programs, and to review, analyze, and interpret experimental results. Ability to draft, execute and record protocols and experiments in a timely manner and maintain an excellent laboratory notebook. Job complexity is high and requires ability to work with high degree of independence. Strong interpersonal, influencing, negotiating and collaboration skills together with evidence of having used these to support problem solving and delivery in a team-oriented, collaborative environment. Proven track record of success in your research and experience preparing written scientific reports and oral presentations. Where can I find out more? Our Social Media, Follow AstraZeneca on LinkedIn https://www.linkedin.com/company/1603/ Follow AstraZeneca on Facebook https://www.facebook.com/astrazenecacareers/ Follow AstraZeneca on Instagram https://www.instagram.com/astrazeneca_careers/?hl=en

Our US Footprint:

Powering Scientific Innovation - YouTube The annual base pay (or hourly rate of compensation) for this position ranges from $116,284 to $174,426. Our positions offer eligibility for various incentives—an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans. As AstraZeneca continues to put patients at the forefront of our mission, we are excited for our move to Kendall Square/Cambridge in 2026.

Find out more information here:

Kendall Square Press Release AstraZeneca is an equal opportunity employer that is committed to diversity and inclusion and providing a workplace that is free from discrimination. AstraZeneca is committed to accommodating persons with disabilities. Such accommodation is available on request in respect of all aspects of the recruitment, assessment and selection process and may be requested by emailing AZCHumanResources@astrazeneca.com. #LI-Hybrid Date Posted 05-May-2026 Closing Date 17-May-2026 Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form. AstraZeneca is a global, science-led, patient-focused biopharmaceutical company. We focus on discovering, developing and commercialising prescription medicines for some of the world's most serious diseases. But we are more than one of the world's leading pharmaceutical companies. At AstraZeneca, we're dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science, challenge convention and unleash your entrepreneurial spirit. To embrace differences and take bold actions to drive the change needed to meet global healthcare and sustainability challenges. There is no better place to make a difference in medicine, patients, and society. An inclusive culture where you will connect different thinking to generate new and valuable opportunities. Where you will find a commitment to lifelong learning, growth and development for all. Our Inclusion & Diversity (I&D) mission is to create an inclusive and equitable environment where people belong, using the power of our diversity to push the boundaries of science to deliver life-changing medicines to patients. Inclusion and diversity are fundamental to the success of our company, because innovation requires breakthrough ideas that only come from a diverse workforce empowered to challenge conventional thinking. We're curious about science and the advancement of knowledge. We find creative ways to approach new challenges. We're driven to make the right choices and be accountable for our actions. As an organisation centred around what makes us human, we put a big focus on people. Across our business, we want colleagues to wake up excited about their day at the office, in the field, or in the lab. Along with our purpose to bring life-changing medicines to people across the globe, we have a promise to you: to help you realise the full breadth of your potential. Here, you'll do work that has the potential to change your life and improve countless others. And, together with your team, you'll shape a culture that unites and inspires us every day. This is your life at AstraZeneca.