Job title Experienced Scientist, In-vivo CAR-T Function Discovery & Pre-Clinical/Clinical Development Sub function Biotherapeutics R D Category Experienced Scientist, Biotherapeutics R D (ST5) Location Spring House / Leiden / United States of America / Netherlands Date posted Aug 13 2026 Requisition number

R-092521

Work pattern Hybrid Work This job posting is anticipated to close on Sep 25 2026. We may however extend this time period, in which case the posting will remain available on www.careers.jnj.com to accept additional applications. Description At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at jnj.com . As guided by Our Credo, Johnson & Johnson is responsible to our employees who work with us throughout the world. We provide an inclusive work environment where each person is considered as an individual. At Johnson & Johnson, we respect the diversity and dignity of our employees and recognize their merit.

Job Function:

Discovery & Pre-Clinical/Clinical Development Job Sub Function:

Biotherapeutics R D Job Category:

Scientific/Technology All Job Posting Locations:

Leiden, Netherlands, Spring House, Pennsylvania, United States of America Job Description:

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at jnj.com . As guided by Our Credo, Johnson & Johnson is responsible to our employees who work with us throughout the world. We provide an inclusive work environment where each person is considered as an individual. At Johnson & Johnson, we respect the diversity and dignity of our employees and recognize their merit. We are searching for the best talent for an Experienced Scientist, In-vivo CAR-T, to be based on-site in Spring House, PA or Leiden, Netherlands.

Purpose:

The Experienced Scientist will support the formulation development, optimization, and scale-up of lentiviral vector (LVV) drug product formulation early to late-stage development. The role combines hands-on laboratory work with strong cross-functional collaboration to ensure robust, scalable, and GMP-ready processes.

Key Responsibilities:

Formulation development and optimization of viral vectors e.g., LVV drug product across early and late development stages Perform hands-on laboratory work including formulation design, optimization, and characterization Analyze and interpret data to support formulation development, optimization, and decision-making Support formulation robustness activities Contribute to scale-up and manufacturing readiness, including support of technology transfer to internal sites or CMOs Collaborate cross-functionally with Analytical Development, Statistical, API, MSAT, Quality, Manufacturing, and Regulatory teams to ensure alignment on formulation strategy and execution of viral vectors Document experimental work and results in accordance with GxP and data integrity requirements Participate in troubleshooting activities and continuous process improvement initiatives

Qualifications:

Required:

B.S. or M.S. with 2-4 years of experience in an appropriate scientific discipline (Life Sciences or Chemical Engineering) is required Relevant experience in formulation development of viral vectors and/or advance therapies Strong hands-on laboratory experience in drug product development of viral vector development and statistics Understanding of process scale-up, technology transfer, and GxP principles Strong scientific problem-solving and data interpretation skills Hands-on, proactive, and detail-oriented approach Ability to work effectively in a cross-functional, matrixed environment Clear and concise communication skills (written and verbal) Ability to manage multiple priorities in a dynamic development environment

Preferred:

Experience with viral vector platforms, LVV in particular, and/or advanced therapies Familiarity with formulation implementation for both early and late-stage development, process validation (e.g., LCPV) and manufacturing support Exposure to both early and late-stage development requirements or commercial readiness activities Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act. Johnson and Johnson is committed to providing an interview process that is inclusive of our applicants' needs. If you are an individual with a disability and would like to request an accommodation, please email the Employee Health Support Center (ra-employeehealthsup@its.jnj.com) or contact AskGS to be directed to your accommodation resource.

Required Skills:

Preferred Skills:

Analytical Reasoning, Biochemistry, Chemistry, Manufacturing, and Control (CMC), Coaching, Collaboration, Conducting Experiments, Data Quality, Drug Discovery Development, Molecular Diagnostics, Patent Applications, Pharmacogenetics, Report Writing, Research Documents, Scientific Research, Technologically Savvy, Written Expression Similar jobs Principal Scientist, In-vivo CAR-T Discovery & Pre-Clinical/Clinical Development Malvern Save Saved Senior Scientist, In-vivo CAR-T Discovery & Pre-Clinical/Clinical Development Spring House Save Saved Scientific Director, Discovery Pharmaceutics Discovery & Pre-Clinical/Clinical Development Spring House Save Saved Careers in North America Discover career opportunities at J&J locations in the United States and Canada. Careers in Europe, Middle East & Africa Learn about working at J&J in our locations across Europe, the Middle East and Africa.