Lantheus (

NASDAQ:

LNTH) is the leading radiopharmaceutical-focused company, delivering life-changing science to enable clinicians to Find, Fight and Follow disease to deliver better patient outcomes. Headquartered in Massachusetts with offices in New Jersey, Canada, Germany, Sweden, Switzerland and United Kingdom, Lantheus has been providing radiopharmaceutical solutions for nearly 70 years. Today, we're expanding our portfolio and pipeline across oncology, neurology and cardiology. Through recent acquisitions, along with strategic partnerships across the life sciences ecosystem, we are accelerating our efforts to advance precision medicine and improve patient outcomes around the world. At Lantheus we are purpose-driven, and every employee plays a vital role in our success. We're dedicated to cultivating a high-growth, forward-thinking culture where innovation thrives and diverse perspectives drive meaningful progress. Join us and be part of a company where your contributions make a real impact, because we know someone's health is in our hands. Summary of role The Clinical Research, Senior Principal Scientist, Oncology is a senior, director-level individual contributor and recognized scientific expert who provides strategic and scientific leadership for oncology clinical development programs. The role shapes clinical research strategy and leads the scientific design, execution, interpretation and communication of company-sponsored clinical research, with particular emphasis on diagnostic imaging, radiopharmaceuticals and molecular imaging. Working in close partnership with the Executive Director, Head of Clinical Development, Oncology, the position translates complex clinical, scientific and competitive information into clear recommendations that support asset, indication and portfolio decisions. The incumbent operates with a high degree of independence, influences cross-functional teams without direct authority and represents Clinical Development in governance, regulatory and external scientific forums. This position is based in Bedford, MA and requires a presence on-site two to three days per week. It is open to applicants authorized to work for any employer within the United States. Responsibilities Serve as the scientific lead for assigned oncology diagnostic development programs and provide expert guidance across Phase I-IV clinical studies, from concept development through study close-out and lifecycle management. Develop and refine clinical development strategies, clinical research plans, target product profiles, study concepts, protocols, endpoints and evidence-generation approaches for oncology indications. Lead the scientific design and interpretation of company-sponsored clinical research in oncology, including clinical study documents, imaging endpoints, biomarker strategies, patient-selection approaches and diagnostic performance considerations. Translate emerging clinical findings into clear, evidence-based strategic recommendations aligned with asset and portfolio objectives; identify key uncertainties, development risks and decision points. Provide scientific leadership to cross-functional teams spanning Clinical Operations, Imaging Sciences and Operations, Biostatistics, Regulatory Affairs, Medical Affairs, Pharmacovigilance, CMC, Translational Sciences and external partners. Guide scientific and clinical aspects of study execution, including protocol interpretation, data review, analysis planning, issue resolution and preparation for governance decisions. Contribute scientific content to regulatory strategies, briefing documents, submissions and responses to health authority questions; support interactions with FDA, EMA and other applicable authorities. Maintain awareness of internal and external scientific, clinical, competitive and regulatory developments that could affect oncology development plans and proactively recommend appropriate action. Build and sustain relationships with investigators, key opinion leaders, cooperative groups, academic collaborators, CROs and other external experts. Lead or contribute to scientific communication and publication plans, including abstracts, manuscripts, congress presentations, data summaries and symposia. Mentor and provide scientific guidance to clinical scientists and project team members; promote rigorous scientific thinking, high-quality decision-making and consistent execution. Implement applicable requirements of the Lantheus quality assurance system and ensure compliance with relevant laws, regulations, guidelines, company policies and procedures. Represent Lantheus at relevant scientific meetings and conferences and communicate key insights to internal stakeholders. Perform other duties as assigned. Basic Qualifications Advanced degree (PhD, PharmD, MD or equivalent) in oncology, medicine, pharmaceutical sciences, molecular biology, imaging sciences or a related scientific discipline. Typically 10 or more years of relevant experience in the pharmaceutical, biotechnology, radiopharmaceutical, diagnostic imaging or clinical research environment, including substantial oncology clinical development experience. Demonstrated expertise in clinical trial design, execution, data interpretation and development strategy across multiple phases of clinical development. Experience with oncology diagnostics, molecular imaging, diagnostic imaging development, radiopharmaceuticals, PET imaging or other relevant imaging modalities. Working knowledge of global clinical development regulations and industry guidelines, including FDA, EMA and ICH requirements. Demonstrated record of sustained scientific accomplishment and recognized expertise, with the ability to apply leading-edge knowledge to complex development questions. Proven ability to lead through influence in a global, cross-functional matrix and to align diverse stakeholders around evidence-based recommendations. Strong strategic judgment and the ability to connect study-level findings with broader asset and portfolio objectives. Excellent written, verbal, presentation and interpersonal communication skills for internal and external stakeholders, including senior leadership. Results-oriented approach with strong initiative, adaptability, organization, prioritization and time-management skills. Ability to work independently with minimal supervision and to travel as required. Preferred Qualifications Direct experience developing oncology diagnostic agents or radiopharmaceutical imaging products from early clinical development through registration or indication expansion. Experience with PET imaging, image analysis, imaging endpoint qualification, biomarker development, precision medicine or theranostic development. Experience presenting clinical development strategy or data to governance bodies and participating in health authority interactions. A strong external scientific network and a publication record relevant to oncology, diagnostic imaging or radiopharmaceutical development. Experience mentoring clinical scientists or providing functional leadership across complex programs. Core Values The ideal candidate will embody Lantheus core values: Let people be their best Respect one another and act as one Learn, adapt, and win Know someone's health is in our hands Own the solution and make it happen The pay range for this position is between $172,000 and $287,000 annually. Actual base pay offered may vary depending on a number of factors such as job-related knowledge, skills and experience. Employees in this position are eligible for a discretionary performance-based cash incentive. Benefits for this position include a comprehensive health benefits package that includes medical, prescription drug, dental, and vision coverage. Other offerings include life and disability benefits, pre-tax accounts, a 401(k) with company contribution, and a variety of other benefits. In addition, employees are eligible for a generous time off package including paid vacation, holidays, sick days, and paid parental leave. Interested candidates can apply at Lantheus.com. Applications for this position will be accepted until September 30, 2026. Lantheus is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's actual or perceived race, color, creed, religion, national origin, ancestry, citizenship status, age, sex or gender (including pregnancy, childbirth, related medical conditions and lactation), gender identity or gender expression, sexual orientation, marital status, military service and veteran status, disability, protected medical condition as defined by applicable state or local law, genetic information, or any characteristic protected under applicable federal, state, or local laws and ordinances. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the Lantheus Talent Acquisition team at talentacquisition@lantheus.com . 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