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Senior Manager, Downstream Science & Applications

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The businesses of Merck KGaA, Darmstadt, Germany

Bedford, MA (In Person)

$166,500 Salary, Full-Time

Posted 1 day ago (Updated 2 hours ago) • Actively hiring

Expires 6/8/2026

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Job Description

Work Your Magic with us! Start your next chapter and join MilliporeSigma. Ready to explore, break barriers, and discover more? We know you've got big plans - so do we! Our colleagues across the globe love innovating with science and technology to enrich people's lives with our solutions in Healthcare, Life Science, and Electronics. Together, we dream big and are passionate about caring for our rich mix of people, customers, patients, and planet. That's why we are always looking for curious minds that see themselves imagining the unimaginable with us. This role does not offer sponsorship for work authorization. External applicants must be eligible to work in the US.
Your Role:
The Downstream Science & Applications team within MilliporeSigma's Downstream Applications R D organization is seeking a Senior Manager to lead a team of senior scientists and engineers focused on advancing applications knowledge for our downstream bioprocessing portfolio. This role sits at the intersection of deep technical expertise, external scientific engagement, and cross-functional collaboration — serving as a critical bridge between our internal R D capabilities and the broader biopharmaceutical community.
Responsibilities:
Scientific & Technical Leadership Serve as a senior subject matter expert (SME) in downstream bioprocessing, providing technical guidance on the most complex and escalated applications challenges across the filtration and chromatography portfolio Lead a team of senior scientists and engineers serving as SMEs and Applications leads on new product development projects to drive early-stage applications development and accelerate commercial readiness and product adoption Define and maintain the team's technical priorities, balancing applications support for new products with legacy product needs, and aligning decisions to broader R D goals and revenue impact Cross-Functional Collaboration Partner with customer facing teams to resolve escalated technical questions and provide expert support Collaborate with the broader innovation and technology pipeline organization to translate external scientific signals into actionable applications development priorities Orchestrate project work across peer R D teams in the role of Applications Lead, ensuring accountability, quality, and strategic alignment on product development deliverables External Engagement & Thought Leadership Represent MilliporeSigma at industry conferences, scientific consortia, and academic collaborations, building and maintaining a broad network of downstream bioprocessing contacts to generate insights that inform the team's technical direction and MilliporeSigma's broader downstream portfolio strategy Author and contribute to the development of publications, application notes, white papers, and other scientific content that establishes MilliporeSigma's thought leadership in downstream bioprocessing
Minimum Qualifications:
Bachelor's degree in Biochemical Engineering, Chemical Engineering, Biochemistry, Biology, or a related life sciences field with 12-15+ years of relevant experience; or Master's degree with 10-12+ years; or PhD with 8-10+ years Demonstrated expertise in downstream bioprocessing, with hands-on experience in chromatography, filtration, or both as an end user or as a downstream applications specialis Experience with biopharmaceutical manufacturing processes and familiarity with relevant modalities including monoclonal antibodies, recombinant proteins, or viral vectors Proven track record of leading and developing technical teams and delivering high-impact scientific results in an R D or applications science environment Strong scientific communication skills with experience presenting at conferences, authoring technical publications, or contributing to external scientific engagement
Preferred Qualifications:
Experience serving in a subject matter expert or applications lead capacity on complex, multi-stakeholder R D projects Established network within the downstream bioprocessing community, including relationships with academic institutions, industry consortia, and key opinion leaders This position is based in Bedford, MA or Damstadt, Germany. Travel of up to 15% may be required to support conference participation, customer engagements, and collaboration with the Darmstadt-based team.
Pay Range for this position:
$114,700- $218,300. The offer range represents the anticipated low and high end of the base pay compensation for this position. The actual compensation offered will be determined by factors such as location, level of experience, education, skills, and other job-related factors. Position may be eligible for sales or performance-based bonuses. Benefits offered by the Company include health insurance, paid time off (PTO), retirement contributions, and other perquisites. For more information click here.
What we offer:
We are curious minds that come from a broad range of backgrounds, perspectives, and life experiences. We believe that this variety drives excellence and innovation, strengthening our ability to lead in science and technology. We are committed to creating access and opportunities for all to develop and grow at your own pace. Join us in building a culture of inclusion and belonging that impacts millions and empowers everyone to work their magic and champion human progress! Apply now and become a part of a team that is dedicated to Sparking Discovery and Elevating Humanity!

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