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Genentech
Senior Machine Learning Scientist, Foundational ML, AI for Biology & Translation (AIBT)
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What they do
A Machine Learning Engineer specializes in designing, building, and deploying machine learning models. They utilize statistical and mathematical techniques, parallelizing processing, hyperparameter tuning, and other optimization methodologies to improve model performance. Responsibilities also include collecting and preprocessing large datasets, conducting exploratory data analysis, working closely with data engineers to understand data requirements, and engineer input variables for machine learning models.
$168,439 / year median in California
Job Description
Senior Machine Learning Scientist, Foundational ML, AI for Biology & Translation (AIBT) Full Time Daly City, CA, United States Posted 1 week ago
Work with and integrate diverse data modalities such as molecular structures, biological sequences, omics data, biochemical readouts, and text.
Bridge cutting-edge AI models and applications supporting target discovery, experimental design, and lab-in-the-loop pipelines.
Scale frontier AI models to massive datasets working at the intersection of deep learning and engineering challenges, focusing on system design, architectural choices, and scalability, in collaboration with engineering and MLOps teams.
Publish in top-tier ML venues and scientific journals, and present results at internal and external conferences and workshops.
Collaborate closely with interdisciplinary and cross-functional teams across gRED and Roche.
Requirements Ph.D. in Computer Science, Machine Learning, Computational Biology, or a related quantitative field0
Excellent knowledge of the theory and practice of deep learning.
Proven experience developing and delivering innovative ML solutions in the areas above.
Excellent Python programming skills, fluency with modern agentic coding environments, and extensive experience with ML frameworks such as PyTorch or JAX.Strong grasp of software engineering, data engineering, and MLOps best practices (e.g., version control, high-performance compute infrastructures, and ML experiment monitoring workflows).Strong publication record and active contribution to research communities, including top-tier ML venues such as NeurIPS, ICML, ICLR, AAAI, ACL, EMNLP, AISTATS, etc. and/or public portfolio of relevant projects (e.g. hosted on GitHub/GitLab).Excellent communication, collaboration, and problem-solving skills.
Nice-to-haves Practical experience bridging innovative ML methods and applications in target/drug discovery.
Experience with biological and chemical modalities and tasks such as molecular structures, single-cell/omics data, perturbation biology, and multimodal biological datasets.
Hands-on experience developing, finetuning, and optimizing LLMs and agentic systems.
Benefits A discretionary annual bonus may be available based on individual and Company performance.
This position also qualifies for the benefits detailed at the link provided below.
Closes:
Sep 29, 2026 Genentech Category Software Engineers/Developers Tags Industry Machine Learning NLP United States Share This Click to share on LinkedIn (Opens in new window) Click to share on Facebook (Opens in new window) Click to share on Twitter (Opens in new window) More Click to share on Reddit (Opens in new window) Click to share on Pinterest (Opens in new window) Click to share on Tumblr (Opens in new window) Click to share on Pocket (Opens in new window) Apply for job Login to bookmark this Job Overview About the position Advances in AI, data, and computational sciences are transforming drug discovery and development. Roche's Research and Early Development organisations at Genentech (gRED) and Pharma (pRED) have demonstrated how these technologies accelerate R D, leveraging data and novel computational models to drive impact. Seamless data sharing and access to models across gRED and pRED are essential to maximising these opportunities. The new Computational Sciences Center of Excellence (CoE) is a strategic, unified group whose goal is to harness the transformative power of data and Artificial Intelligence (AI) to assist our scientists in both pRED and gRED to deliver more innovative and transformative medicines for patients worldwide. Responsibilities Design and build foundation models to support target and drug discovery, with a focus on large-scale representation learning, multimodal generative models, LLMs, AI agents, and reinforcement learning.Work with and integrate diverse data modalities such as molecular structures, biological sequences, omics data, biochemical readouts, and text.
Bridge cutting-edge AI models and applications supporting target discovery, experimental design, and lab-in-the-loop pipelines.
Scale frontier AI models to massive datasets working at the intersection of deep learning and engineering challenges, focusing on system design, architectural choices, and scalability, in collaboration with engineering and MLOps teams.
Publish in top-tier ML venues and scientific journals, and present results at internal and external conferences and workshops.
Collaborate closely with interdisciplinary and cross-functional teams across gRED and Roche.
Requirements Ph.D. in Computer Science, Machine Learning, Computational Biology, or a related quantitative field0
- 2+ years of industry or post-doc experienceProven track record advancing ML models in research and/or industry settings, particularly in large-scale representation learning, multimodal generative models, LLMs, AI agents, and reinforcement learning.
Excellent knowledge of the theory and practice of deep learning.
Proven experience developing and delivering innovative ML solutions in the areas above.
Excellent Python programming skills, fluency with modern agentic coding environments, and extensive experience with ML frameworks such as PyTorch or JAX.Strong grasp of software engineering, data engineering, and MLOps best practices (e.g., version control, high-performance compute infrastructures, and ML experiment monitoring workflows).Strong publication record and active contribution to research communities, including top-tier ML venues such as NeurIPS, ICML, ICLR, AAAI, ACL, EMNLP, AISTATS, etc. and/or public portfolio of relevant projects (e.g. hosted on GitHub/GitLab).Excellent communication, collaboration, and problem-solving skills.
Nice-to-haves Practical experience bridging innovative ML methods and applications in target/drug discovery.
Experience with biological and chemical modalities and tasks such as molecular structures, single-cell/omics data, perturbation biology, and multimodal biological datasets.
Hands-on experience developing, finetuning, and optimizing LLMs and agentic systems.
Benefits A discretionary annual bonus may be available based on individual and Company performance.
This position also qualifies for the benefits detailed at the link provided below.
Company:
Genentech Qualifications:
Language requirements: Specific requirements: Educational level: Level of experience (years): Senior (5+ years of experience) Tagged as: Industry , Machine Learning , NLP , United States About Genentech Genentech is a biotechnology research company that specializes in genetic testing and personalized medicines. Related Jobs AI & Machine Learning Engineering Consultant- Manager
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