Principal Scientist - Cancer Early Detection

Principal Scientist - Cancer Early Detection
Employer
InVitro Cell Research, LLC
Location
Englewood, NJ
Start date
Mar 10, 2026
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Job Details ICR's Cancer Early Detection program is focused on building early warning systems out of arrays of blood- and urine-based biomarkers from cancer patients and healthy controls, mostly stages zero, one and two. We're using machine learning to predict cancer signatures to enable early intervention when cancer is most treatable. We're hiring a Principal Scientist to lead our Cancer Early Detection Team. With ICR, you'll get to: Lead a cutting-edge cancer biomarkers group with the goal of detecting cancer at its earliest stages
Contribute highly practical and readily translatable pan-cancer screening/early detection, diagnostic, prevention and therapeutic ideas
Quantify and track cancer biomarkers, including CTCs, cfDNA, serum, plasma, and urine proteins, RNA, metabolites, driver-gene mutations, epigenetic modifications, etc
Collaborate with ICR's Biomarkers Team to perform molecular and cellular cancer prevention screening assays, under a personalized medicine paradigm Please apply if you have: A PhD, MD or both
At least 10 years of cancer research experience, preferably in early detection and biomarkers
Current and in-depth knowledge of pan-cancer: screening, early detection, biomarkers, diagnostic prediction, genetics, prevention, and chemical and vaccine-therapeutics (practical and experimental) Programming experience in R and Python
Solid grasp of biostatistics, especially probability theory
Experience with prediction modeling and machine learning, including experience using proper scoring rules Ideally, you'll also have: Expert knowledge and understanding of worldwide cancer biomarker and detection assay development pipelines Experience with cell-based assays, immunofluorescent microscopy, qPCR, flow cytometry, single-cell genomics, RNAseq, cell culture, organoid culture, Illumina NextSeq 550, DNA methylation sequencing, ddPCR, Luminex, clinical chemistry instrumentation, Kryptor, Access 2, robotic liquid handling (e.g. Tecan), Vortex, and DepArray
Experience with protein, RNA, and small metabolite cancer biomarker analysis And you'll need: An easygoing, friendly personality
The ability to work in the United States without sponsorship Salary Starting base pay range: $165,000/yr - $205,000/yr Starting additional compensation range: $7,500/yr - $20,000/yr Starting position title and compensation are commensurate with experience. Company InVitro Cell Research, LLC (ICR) is a privately funded company focused on regenerative and preventive personalized medicine. We are dedicated to discovering and developing interventions to slow and reverse biological aging and prevent major age-related diseases. ICR has a small-group vibe and a highly collaborative work environment. We invest in our scientists, providing them the state-of-the-art resources they need to leverage their time and skills most effectively, empowering small teams to accomplish the amazing and advance our mission. Our mission is to research ways to repair aging people, fast. Company info