Description We are seeking a Bioinformatician to implement, validate, optimize, and maintain robust bioinformatics workflows. This role is central to ensuring that analytical pipelines meet stringent scientific, quality, and regulatory standards. The ideal candidate combines strong software development skills with hands-on experience in Linux-based bioinformatics environments. Responsibilities Implement NGS bioinformatics pipelines, including annotation, QC workflows, and downstream analytical components Own end-to-end validation of implemented pipelines, ensuring they meet scientific and regulatory requirements Execute software verification and validation (SV&V) protocols and maintain thorough documentation of all results Evaluate new tools, algorithms, and software for integration into analytical workflows Troubleshoot pipeline failures and drive root-cause analyses Ensure reproducibility, scalability, and robustness of computational workflows Partner with wet-lab teams, quality assurance, clinical operations, and product management to align implementation and validation objectives with project timelines and business needs Maintain detailed records of implementation, validation activities, version control, and release notes Prepare documentation in support of internal quality audits Other related duties as assigned. Qualifications B.S. in Biological Sciences, Bioinformatics, Computer Sciences, Statistics or related discipline; M.S. preferred 3 years' experience required; 2+ years of software development experience in a Linux environment highly preferred Programming experience in Python, R, or Bash highly preferred Solid understanding of NGS technologies and analytical methods, including alignment, QC metrics, and annotation tools Proficiency with workflow management systems such as Nextflow, Snakemake, or WDL/Cromwell Strong working knowledge of Linux system administration Experience implementing and validating bioinformatics tools in regulated or semi-regulated environments Employer Description Strength through Unity and Inclusion The Mount Sinai Health System is committed to fostering an environment where everyone can contribute to excellence. We share a common dedication to delivering outstanding patient care. When you join us, you become part of Mount Sinai's unparalleled legacy of achievement, education, and innovation as we work together to transform healthcare. We encourage all team members to actively participate in creating a culture that ensures fair access to opportunities, promotes inclusive practices, and supports the success of every individual. At Mount Sinai, our leaders are committed to fostering a workplace where all employees feel valued, respected, and empowered to grow. We strive to create an environment where collaboration, fairness, and continuous learning drive positive change, improving the well-being of our staff, patients, and organization. Our leaders are expected to challenge outdated practices, promote a culture of respect, and work toward meaningful improvements that enhance patient care and workplace experiences. We are dedicated to building a supportive and welcoming environment where everyone has the opportunity to thrive and advance professionally. Explore this opportunity and be part of the next chapter in our history. About the

Mount Sinai Health System:

Mount Sinai Health System is one of the largest academic medical systems in the New York metro area, with more than 48,000 employees working across eight hospitals, more than 400 outpatient practices, more than 300 labs, a school of nursing, and a leading school of medicine and graduate education. Mount Sinai advances health for all people, everywhere, by taking on the most complex health care challenges of our time — discovering and applying new scientific learning and knowledge; developing safer, more effective treatments; educating the next generation of medical leaders and innovators; and supporting local communities by delivering high-quality care to all who need it. Through the integration of its hospitals, labs, and schools, Mount Sinai offers comprehensive health care solutions from birth through geriatrics, leveraging innovative approaches such as artificial intelligence and informatics while keeping patients' medical and emotional needs at the center of all treatment. The Health System includes more than 9,000 primary and specialty care physicians; 13 joint-venture outpatient surgery centers throughout the five boroughs of New York City, Westchester, Long Island, and Florida; and more than 30 affiliated community health centers. We are consistently ranked by U.S. News & World Report's Best Hospitals, receiving high "Honor Roll" status, and are highly ranked: No. 1 in Geriatrics, top 5 in Cardiology/Heart Surgery, and top 20 in Diabetes/Endocrinology, Gastroenterology/GI Surgery, Neurology/Neurosurgery, Orthopedics, Pulmonology/Lung Surgery, Rehabilitation, and Urology. New York Eye and Ear Infirmary of Mount Sinai is ranked No. 12 in Ophthalmology. U.S. News & World Report's "Best Children's Hospitals" ranks Mount Sinai Kravis Children's Hospital among the country's best in several pediatric specialties. The Icahn School of Medicine at Mount Sinai is ranked No. 11 nationwide in National Institutes of Health funding and in the 99th percentile in research dollars per investigator according to the Association of American Medical Colleges. Newsweek's "The World's Best Smart Hospitals" ranks The Mount Sinai Hospital as No. 1 in New York and in the top five globally, and Mount Sinai Morningside in the top 20 globally. Equal Opportunity Employer The Mount Sinai Health System is an equal opportunity employer, complying with all applicable federal civil rights laws. We do not discriminate, exclude, or treat individuals differently based on race, color, national origin, age, religion, disability, sex, sexual orientation, gender, veteran status, or any other characteristic protected by law. We are deeply committed to fostering an environment where all faculty, staff, students, trainees, patients, visitors, and the communities we serve feel respected and supported. Our goal is to create a healthcare and learning institution that actively works to remove barriers, address challenges, and promote fairness in all aspects of our organization. Compensation The Mount Sinai Health System (MSHS) provides salary ranges that comply with the New York City Law on Salary Transparency in Job Advertisements. The salary range for the role is $65000.17 - $91114.4 Annually. Actual salaries depend on a variety of factors, including experience, education, and operational need. The salary range or contractual rate listed does not include bonuses/incentive, differential pay or other forms of compensation or benefits.

Qualifications:

B.S. in Biological Sciences, Bioinformatics, Computer Sciences, Statistics or related discipline; M.S. preferred 3 years' experience required; 2+ years of software development experience in a Linux environment highly preferred Programming experience in Python, R, or Bash highly preferred Solid understanding of NGS technologies and analytical methods, including alignment, QC metrics, and annotation tools Proficiency with workflow management systems such as Nextflow, Snakemake, or WDL/Cromwell Strong working knowledge of Linux system administration Experience implementing and validating bioinformatics tools in regulated or semi-regulated environments