Find & Apply For General Manager Jobs in Needham, Massachusetts

We are looking for a strategic and hands-on technology executive to guide the company's IT direction during a pivotal stage of growth in Needham, Massachusetts. This leader will shape enterprise systems, cybersecurity, infrastructure, data capabilities, and digital innovation while partnering closely with senior leadership and cross-functional teams. The role is responsible for building scalable, compliant, and business-ready technology operations that support clinical development and commercial readiness.

Responsibilities:

• Define and lead the enterprise technology strategy, aligning platforms, processes, and investments with organizational priorities and long-term growth plans.
• Direct day-to-day IT operations across internal staff and external service providers, ensuring reliable support, strong performance, and clear accountability.
• Oversee regulated business systems and technology environments used across clinical, quality, regulatory, finance, HR, supply chain, technical operations, commercial, and research functions.
• Strengthen cybersecurity, identity and access controls, risk management, and disaster recovery capabilities to protect systems, data, and business continuity.
• Manage the Microsoft 365 and cloud ecosystem, driving secure, efficient, and scalable use of collaboration tools, infrastructure, and SaaS applications.
• Establish data governance practices and expand analytics and AI capabilities that improve decision-making and operational insight across the organization.
• Partner with business leaders to prepare technology operations for commercial launch activities and evolving organizational demands.
• Lead vendor strategy, contract oversight, and service delivery management to maximize value, reduce risk, and maintain dependable external partnerships.
• Ensure IT practices, documentation, and systems remain aligned with GxP expectations, 21 CFR Part 11 requirements, and other applicable regulatory standards.