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Job title Senior Scientist, Bioconjugates, Downstream Processing Function Discovery & Pre-Clinical/Clinical Development Sub function Biotherapeutics R D Category Senior Scientist, Biotherapeutics R D (ST6) Location Pennsylvania (Any City) / United States of America Date posted Oct 02 2026 Requisition number

R-101915

Work pattern Fully Onsite This job posting is anticipated to close on Oct 16 2026. We may however extend this time period, in which case the posting will remain available on www.careers.jnj.com to accept additional applications. Description At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at jnj.com . As guided by Our Credo, Johnson & Johnson is responsible to our employees who work with us throughout the world. We provide an inclusive work environment where each person is considered as an individual. At Johnson & Johnson, we respect the diversity and dignity of our employees and recognize their merit.

Job Function:

Discovery & Pre-Clinical/Clinical Development Job Sub Function:

Biotherapeutics R D Job Category:

Scientific/Technology All Job Posting Locations:

Pennsylvania (Any City) About Innovative Medicine Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow. Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.

Learn more at https:

//www.jnj.com/innovative-medicine We are searching for the best talent for Senior Scientist, Bioconjugates, Downstream Processing.

Purpose:

The Senior Scientist, Bioconjugates, Downstream Processing leads and performs process development activities for antibodies and bioconjugates such as targeted lipid-nano particles (tLNP), antibody-drug conjugate (ADC), antibody-oligo conjugate (AOC), and antibody-peptide conjugate (APC) within the API-Large Molecule group in Malvern, PA.

You will be responsible for:

Lead and participate in experimental design, execute planned experiments, and optimize process steps for the target process scale, including laboratory- and occasional pilot-scale conjugation reactions, chromatography, and TFF filtration. Lead the design and execution of development studies to identify appropriate conditions and establish ranges for critical process parameters across chromatography, filtration, and conjugation reaction process steps. Record and analyze experimental data, verify data integrity and accuracy, report and summarize findings for the project team, draft technical documents, and perform technology transfers to collaboration partners. Work collaboratively in a team environment and contribute independently to meet project timelines and objectives. Qualifications /

Requirements:

PhD (preferably in Chemical Engineering or Biological Sciences or Biochemistry or other equivalent major) with at least 3 years of relevant post-doctoral experience OR MS (Preferably in Chemical Engineering or Biological Sciences or Biochemistry or other equivalent major) and with at least 12 years of relevant experience OR a BS (preferably in Chemical Engineering or Biological Sciences or Biochemistry or other equivalent major) and with at least 15 years of relevant experience is required. Knowledge and hands-on laboratory experience in downstream processing, purification of antibodies/recombinant protein therapeutics, and production of bioconjugates (such as tLNP, ADC or other equivalent conjugates), in particular chromatography, filtration and conjugation, are required. Exposure to analytical method development for in-process methods is preferred. The candidate must be highly organized and capable of managing/pursuing multiple projects independently. Good written and verbal communication skills are required. Experience maintaining written records of work in the form of (electronic) notebooks, technical reports and protocols is required. Data reporting, ability to present findings to management, and experience with team-based collaborations is a must. Occasional weekend work may be required. Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act. Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants' needs. If you are an individual with a disability and would like to request an accommodation, external applicants please contact us via https://www.jnj.com/contact-us/careers , internal employees contact AskGS to be directed to your accommodation resource. #LI-Onsite About Innovative Medicine Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow. Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.

Learn more at https:

//www.jnj.com/innovative-medicine We are searching for the best talent for Senior Scientist, Bioconjugates, Downstream Processing.

Purpose:

The Senior Scientist, Bioconjugates, Downstream Processing leads and performs process development activities for antibodies and bioconjugates such as targeted lipid-nano particles (tLNP), antibody-drug conjugate (ADC), antibody-oligo conjugate (AOC), and antibody-peptide conjugate (APC) within the API-Large Molecule group in Malvern, PA.

You will be responsible for:

Lead and participate in experimental design, execute planned experiments, and optimize process steps for the target process scale, including laboratory- and occasional pilot-scale conjugation reactions, chromatography, and TFF filtration. Lead the design and execution of development studies to identify appropriate conditions and establish ranges for critical process parameters across chromatography, filtration, and conjugation reaction process steps. Record and analyze experimental data, verify data integrity and accuracy, report and summarize findings for the project team, draft technical documents, and perform technology transfers to collaboration partners. Work collaboratively in a team environment and contribute independently to meet project timelines and objectives. Qualifications /

Requirements:

PhD (preferably in Chemical Engineering or Biological Sciences or Biochemistry or other equivalent major) with at least 3 years of relevant post-doctoral experience OR MS (Preferably in Chemical Engineering or Biological Sciences or Biochemistry or other equivalent major) and with at least 12 years of relevant experience OR a BS (preferably in Chemical Engineering or Biological Sciences or Biochemistry or other equivalent major) and with at least 15 years of relevant experience is required. Knowledge and hands-on laboratory experience in downstream processing, purification of antibodies/recombinant protein therapeutics, and production of bioconjugates (such as tLNP, ADC or other equivalent conjugates), in particular chromatography, filtration and conjugation, are required. Exposure to analytical method development for in-process methods is preferred. The candidate must be highly organized and capable of managing/pursuing multiple projects independently. Good written and verbal communication skills are required. Experience maintaining written records of work in the form of (electronic) notebooks, technical reports and protocols is required. Data reporting, ability to present findings to management, and experience with team-based collaborations is a must. Occasional weekend work may be required. Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act. Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants' needs. If you are an individual with a disability and would like to request an accommodation, external applicants please contact us via https://www.jnj.com/contact-us/careers , internal employees contact AskGS to be directed to your accommodation resource. #

LI-Onsite Required Skills:

Preferred Skills:

Analytical Reasoning, Biochemistry, Chemistry, Manufacturing, and Control (CMC), Coaching, Consulting, Critical Thinking, Drug Discovery Development, Emerging Technologies, Molecular Diagnostics, Pharmacogenetics, Pharmacovigilance, Process Improvements, Quality Assurance (QA), Relationship Building, Research Documents, Scientific Research, Technologically Savvy About Innovative Medicine Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow. Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.

Learn more at https:

//www.jnj.com/innovative-medicine We are searching for the best talent for Senior Scientist, Bioconjugates, Downstream Processing.

Purpose:

The Senior Scientist, Bioconjugates, Downstream Processing leads and performs process development activities for antibodies and bioconjugates such as targeted lipid-nano particles (tLNP), antibody-drug conjugate (ADC), antibody-oligo conjugate (AOC), and antibody-peptide conjugate (APC) within the API-Large Molecule group in Malvern, PA.

You will be responsible for:

Lead and participate in experimental design, execute planned experiments, and optimize process steps for the target process scale, including laboratory- and occasional pilot-scale conjugation reactions, chromatography, and TFF filtration. Lead the design and execution of development studies to identify appropriate conditions and establish ranges for critical process parameters across chromatography, filtration, and conjugation reaction process steps. Record and analyze experimental data, verify data integrity and accuracy, report and summarize findings for the project team, draft technical documents, and perform technology transfers to collaboration partners. Work collaboratively in a team environment and contribute independently to meet project timelines and objectives. Qualifications /

Requirements:

PhD (preferably in Chemical Engineering or Biological Sciences or Biochemistry or other equivalent major) with at least 3 years of relevant post-doctoral experience OR MS (Preferably in Chemical Engineering or Biological Sciences or Biochemistry or other equivalent major) and with at least 12 years of relevant experience OR a BS (preferably in Chemical Engineering or Biological Sciences or Biochemistry or other equivalent major) and with at least 15 years of relevant experience is required. Knowledge and hands-on laboratory experience in downstream processing, purification of antibodies/recombinant protein therapeutics, and production of bioconjugates (such as tLNP, ADC or other equivalent conjugates), in particular chromatography, filtration and conjugation, are required. Exposure to analytical method development for in-process methods is preferred. The candidate must be highly organized and capable of managing/pursuing multiple projects independently. Good written and verbal communication skills are required. Experience maintaining written records of work in the form of (electronic) notebooks, technical reports and protocols is required. Data reporting, ability to present findings to management, and experience with team-based collaborations is a must. Occasional weekend work may be required. Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act. Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants' needs. If you are an individual with a disability and would like to request an accommodation, external applicants please contact us via https://www.jnj.com/contact-us/careers , internal employees contact AskGS to be directed to your accommodation resource. #LI-Onsite Similar jobs Principal Scientist, Protein Purification, Team Lead Discovery & Pre-Clinical/Clinical Development Spring House Save Saved Senior Scientist, Protein Analytical Development, Characterization Discovery & Pre-Clinical/Clinical Development Malvern Save Saved Senior Scientist, Pharmacometrics Discovery & Pre-Clinical/Clinical Development Raritan / Spring House Save Saved Careers in North America Discover career opportunities at J&J locations in the United States and Canada.