Scope of the role:

\nThe Senior Director, Commercial Analytics & Operations, serves as a strategic commercial leader responsible for defining and executing the field force effectiveness strategy for a rare disease portfolio. This role oversees customer targeting and segmentation, sales force sizing and deployment, territory alignment, incentive compensation, commercial performance analytics, and launch readiness initiatives. The Senior Director partners closely with Commercial Leadership, Marketing, Market Access, Finance, Human Resources, Medical Affairs, Data & Analytics Providers, and Executive Management to optimize resource allocation, maximize field force productivity, and accelerate business performance. This role is critical in ensuring that commercial investments are aligned with corporate strategy and that field teams are equipped with the insights, tools, and incentives necessary to achieve organizational objectives in highly specialized rare disease markets. This scope aligns with commercial operations activities documented internally for launch readiness, field force sizing, targeting and alignment, incentive compensation, and sales force effectiveness. The Senior Director will manage internal staff, contractors, consultants, and external vendors, as well as oversee significant commercial operations budgets and strategic investments.

Your key responsibilities:

\nCommercial Operations Strategy Serve as a key member of the Analytics and Operations Team, influencing strategic decisions related to deployment, investment prioritization, customer engagement, and growth\nTranslate corporate, brand, and launch objectives into scalable commercial operations programs\nLead and maintain a high-performing team focused on operational excellence, analytics, and continuous improvement\nEstablish operational frameworks and cadence that ensure transparency, accountability, and alignment across commercial functions Sales Force Targeting, Segmentation & Customer Strategy Own enterprise-wide customer segmentation and targeting strategies across healthcare providers, institutional accounts, and payer networks\nLead development of data-driven methodologies to prioritize customers based on market opportunity, patient flow dynamics, prescribing behavior, and treatment adoption potential\nEstablish targeting governance, refresh processes, and performance measurement frameworks\nPartner with Sales, Marketing, and Market Access leadership to optimize customer engagement models and call planning strategies\nEnsure segmentation and targeting approaches evolve with market conditions and launch-stage requirements Sales Force Sizing, Structure & Alignment Lead all sales force design activities including sizing, deployment, territory alignment, organizational structure, and resource allocation\nDevelop strategic recommendations regarding field force expansion, realignment, role specialization, and deployment models\nOversee territory design and optimization initiatives balancing opportunity, workload, access, travel burden, and organizational efficiency\nDrive alignment decisions that improve customer coverage and ensure equitable territory potential\nLead field deployment strategies for new product launches Incentive Compensation & Performance Management Maintain the company's incentive compensation approach, governance model, and performance measurement framework\nLead design and optimization of incentive compensation plans that drive strategic objectives while maintaining simplicity, fairness, and compliance\nOversee goal setting and allocation, territory indexing, and performance measurement methodologies\nReview compensation effectiveness and make recommendations for plan enhancements based on business outcomes and competitive benchmarking\nEnsure accurate administration, governance, and audit readiness of all incentive compensation programs. Internal guidance documents emphasize governance, fairness, transparency, quota setting, and incentive plan design principles Commercial Analytics & Business Insights Lead commercial analytics capabilities that deliver actionable business insights across sales, market access, targeting, deployment, and incentive compensation\nFacilitate development of dashboards, performance reporting, forecasting tools, and executive business reviews\nLead strategic analyses that support business planning, launch readiness, organizational investments, and resource allocation decisions\nProvide executive-level insights regarding market dynamics, customer engagement effectiveness, field productivity, and commercial performance trends\nChampion data-driven decision-making throughout the commercial organization Launch Excellence & Rare Disease Commercialization Execute launch readiness plans encompassing field force deployment, targeting, incentive compensation, analytics, reporting, and operational infrastructure\nDevelop scalable operating models and standard reporting supporting launch, and growth-stage commercialization\nIdentify operational risks and mitigation strategies that support launch success and sustainable growth Cross-Functional Leadership Serve as a primary commercial operations partner to: Commercial Leadership, Sales Leadership, Marketing, Market Access, Finance, Human Resources, Medical Affairs, Compliance, Executive Leadership Team\nInfluence organizational strategy through data-driven recommendations and executive-level communication\nLead complex, cross-functional initiatives spanning multiple business functions and external partners\nManage strategic vendor relationships supporting analytics, incentive compensation, CRM, data acquisition, and commercial operations Compliance, Governance & Risk Management Ensure all commercial operations activities comply with company policy, legal requirements, industry regulations, and compliance standards\nEstablish governance frameworks for targeting, territory alignment, incentive compensation, data management, and performance reporting\nEnsure defensible methodologies, documentation, audit readiness, and data integrity standards across all processes\nPromote a culture of operational excellence, compliance, and ethical business conduct Who you are: Bachelor's degree required in Business, Economics, Analytics, Life Sciences, Mathematics, Finance, or related field; MBA, MPH, MS, or other advanced degree strongly preferred\n12+ years of progressive pharmaceutical, biotechnology, or healthcare commercial operations experience\n5+ years of leadership experience managing on- and off-shore teams and enterprise-wide initiatives\nSignificant experience supporting specialty, orphan, rare disease, or biologic product launches\nAbility to work onsite in the Morristown, NJ office on a hybrid basis (minimum 3 days per week)\nAbility to travel as needed, up to 10%, potentially including overnight/weekend travel

Why Join Alfasigma:

\nAt Alfasigma, we foster a culture where the courage to innovate is key to our success.\nWe offer a competitive salary, comprehensive benefits, and extensive opportunities for professional growth and development. Our commitment to people and patients is at the heart of everything we do. We value diversity and welcome individuals with unique perspectives and experiences. We believe that open-mindedness, collaboration, and a shared passion for innovation are essential to achieving meaningful progress. Join Alfasigma and become part of a forward-thinking team dedicated to shaping the future of the pharmaceutical industry.

Compensation & Benefits:

\nThe anticipated salary range for this position is $240,000 to $300,000. This represents the anticipated low and high end of the salary range for this position. Actual salaries may vary based on various factors including, but not limited to, experience, skillset, and performance. The salary range listed is just one component of our total compensation package. Alfasigma US also provides a competitive suite of benefits, including:\n

401(k) plan with company match\n
Rewards and recognition program\n
Health care benefits (medical, prescription drugs, dental, and vision insurance)\n
Short and long-term disability coverage provided\n
Plan coverage for domestic partners\n
Paid parental leave benefits and adoption assistance\n
Tuition reimbursement assistance\n
A generous Paid Time Off program that includes 20 vacation days, 11 holidays, 4 personal days, and 2 volunteer days per calendar year\n
Numerous well-being and work/life programs EEO Statement\nEmployment decisions at the Company are made without unlawful regard to race, color, religion, creed, national origin, alienage or citizenship status, sex (including gender, pregnancy, childbirth or medical conditions related to pregnancy or childbirth), gender identity or expression, sexual orientation, national origin, ethnicity, age, physical or mental disability, legally protected genetic information, marital or partnership status, sexual and reproductive health decisions, military or veteran status, or any other status protected by applicable federal, state, or local law.

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Senior Director, Commercial Analytics & Operations (USA Rare Disease)