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LatchBio

Bioinformatics Engineer - Function

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What they do

A Biomedical Engineer designs solutions to problems in medicine and biology to improve patient care. Combines engineering with medical and biological knowledge. May develop medical products designed to replace biological functions, such as prosthetic limbs or artificial hearts, or design equipment such as X-rays and surgical tools.

$113,160 / year median in California

+4% projected growth

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Job Description

As molecular data generation and frontier model intelligence grows, new approaches to data analysis are needed across the biotech industry. Latch is building intelligent, high performance agents for biological data analysis, empowering over 5,000 scientists across 150+ R&D labs to handle data from instrument-to-insights. We're seeking a BioEngineer for Functional Biology to join our FunctionBench, working at the frontier of what artificial intelligence can achieve in biology. About the Role You will contribute to our technical approach for evaluating how AI agents reason through biological function: recovering and interpreting experimental evidence to make informed decisions about binding, stability, immune escape, viral fitness, toxin potency, and protein design. Working with software engineers and biologists, you'll build ground-truth benchmark datasets (drawn from real discovery and development programs) that rigorously test whether agents can perform the critical quantitative reasoning steps that human scientists execute: parsing noisy assay data, inferring mechanism, and predicting functional outcomes. Your hands-on expertise in functional biology assays and computational modeling will define how we measure agent capability in understanding and reasoning about biological sequences and structures. Requirements Hands-on experience in biochemistry, biophysics, bioengineering, synthetic biology, virology, microbiology, immunology, or a closely related field Direct experience generating or analyzing functional-assay data (titration curves, deep mutational scanning, potency assays, cell-based readouts, etc.) OR computational protein design Comfort with quantitative modeling applied to noisy experimental data Proficiency in Python and/or R for data analysis & visualization Familiarity with at least one of: Binding affinity & stability (Tite-seq, SPR/BLI, biophysical characterization) Immune escape & immunogenicity assessment Viral fitness, host-range, or zoonotic spillover evaluation Toxin potency or antimicrobial/antiviral resistance Protein design or structure-guided functional design Gain-of-function or molecular mechanism investigation Nice-to-Have Experience designing or troubleshooting functional assays (ELISA, cell-based, biochemical) Familiarity with deep learning applied to protein design or functional prediction Exposure to regulatory or safety considerations in bioengineering Compensation & Logistics OTE 120k - 180k - Performance based pay Free meals onsite (lunch and dinner) Waterfront office in China Basin, San Francisco Full-time, in-person (can be remote)