Hi there, I'm Siddhi, Talent Expert with Collabera LLC. Hope this message finds you well! We're actively hiring for top performers, and I think you could be a great fit. Why apply now? Positions are filling fast, and we're hiring immediately. If this resonates with you, I'd love to chat about how your background aligns with this opportunity. Let's explore if it's the right next move for you. Ready to connect?

Email:

siddhi.kadakia@collabera.com or

Phone:

(847

•440-1112

Position Details:

Client Industry:

Pharmaceutical/Medical Device/Biotechnology Title:

Scientist II

•CMC /

Protein Purification Location:

South San Francisco, CA 94080

Duration:

6 months ++ possibility of extension based on performance and business needs

Shift:

USA Standard Business Hours Shift Pay Rate:

$55

•62/hr Role Overview CMC Biologics is establishing a new scale-up purification laboratory in South San Francisco. The scientist will support lab startup and day-to-day scale-up/pilot purification activities, with significant hands-on responsibility for buffer preparation, chromatography, TFF operations, equipment setup/troubleshooting, SOP development, documentation, and technical reporting. The ideal candidate has biologics/protein purification experience in a GMP, pilot, or scale-up environment, preferably with experience spanning purification from harvest through UF/DF and pilot operations around 50 L-1,000 L bioreactor scale. Ideal Candidate A BS/MS-level scientist with hands-on biologics downstream purification experience who has worked in a GMP, pilot, or scale-up environment. The strongest profile will have antibody/protein purification experience across multiple unit operations, direct operation of ÄKTA and TFF equipment, pilot-scale exposure, equipment troubleshooting capability, and experience establishing SOPs/documentation in a laboratory setting. Core Requirements BS with approximately 5-7 years relevant experience OR MS with approximately 2+ years relevant experience. Degree in Chemical Engineering, Chemistry, Biochemistry, Bioengineering, or related discipline. Hands-on CMC/biologics protein purification or related downstream process experience. Experience in a GMP facility, pilot laboratory, or scale-up environment. Hands-on experience with chromatography and filtration unit operations, including: Protein A / affinity chromatography Ion exchange chromatography (CEX/AEX/IEX) Hydrophobic interaction chromatography (HIC) Mixed-mode chromatography (MM) preferred Depth filtration Virus/sterile filtration Nanofiltration

TFF / UF-DF

Experience operating larger-scale bioprocess equipment, including chromatography systems and TFF skids. Ability to work hands-on in a primarily laboratory-based environment. Experience authoring SOPs, technical reports, and maintaining detailed ELN records. Strong troubleshooting, experimental design, analytical, planning, and scientific communication skills. Key Responsibilities Perform and support scale-up protein purification processes from harvest through UF/DF. Prepare buffers at laboratory/pilot scale. Set up, operate, troubleshoot, and maintain chromatography systems, TFF skids, filtration systems, mixers, tanks, pumps, and single-use assemblies. Perform pre-run readiness activities, including equipment setup, column packing/qualification, buffer/media verification, and raw-material staging. Support GLP toxicology material production and transfers to GMP manufacturing for clinical material. Develop and maintain SOPs for laboratory equipment and processes. Document experimental/process activities in ELN and prepare technical reports. Present technical findings to project teams/stakeholders. Support establishment and operationalization of the new purification laboratory. Collaborate cross-functionally toward project timelines and deliverables. Preferred Experience Antibody or antibody-like molecule purification. End-to-end purification experience from harvest through UF/DF. Pilot-scale experience, preferably 50 L-1,000 L bioreactor scale. Recent/current GMP or pilot-lab experience. Process development experience, including candidates with primarily bench-scale development experience.

Hands-on experience with:

ÄKTA Ready

•primary system ÄKTA Process ÄKTA Avant ÄKTA Pure Potentially ÄKTA Pilot 600 Lab startup/setup experience, including equipment installation/setup, SOP creation, and documentation systems. HPLC, LAL, ELISA, high-throughput technologies, or automation experience.

Highest priority:

Recent/current GMP, pilot, or scale-up laboratory experience. Hands-on biologics/protein or antibody purification. Multiple purification unit operations, ideally harvest through UF/DF.

Hands-on chromatography:

Protein A, IEX, and/or HIC. ÄKTA and TFF equipment operation. Larger-scale/pilot operations, ideally 50 L-1,000 L. Equipment troubleshooting and laboratory setup. SOP, ELN, technical report, and presentation experience

Benefits:

The Company offers the following benefits for this position, subject to applicable eligibility requirements: medical insurance, dental insurance, vision insurance, 401(k) retirement plan, life insurance, long-term disability insurance, short-term disability insurance, paid parking/public transportation, (paid time , paid sick and safe time , hours of paid vacation time, weeks of paid parental leave, paid holidays annually

•These all are subject to applicable eligibility).