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Process Engineer, Downstream

Job

US01 Agilent Technologies, Inc.

Frederick, CO (In Person)

$159,080 Salary, Full-Time

Posted 2 days ago (Updated 10 hours ago) • Actively hiring

Expires 6/15/2026

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Job Description

Job Description Agilent inspires and supports discoveries that advance the quality of life. We provide life science, diagnostic and applied market laboratories worldwide with instruments, services, consumables, applications and expertise. Agilent enables customers to gain the answers and insights they seek•so they can do what they do best: improve the world around us. Information about Agilent is available at www.agilent.com. Want to take your knowledge and experience further? Ready to provide technical leadership and make key decisions? This is your opportunity•not only to join a committed, professional, and forward-thinking team but also to lead in the design and implementation of complex manufacturing processes and transform broad concepts into structured results-focused projects. Join a growing team with this exciting new opportunity for an expert level Downstream Process Engineer. Work on a dynamic, fast-paced, large capacity oligonucleotide API production facility design and construction project. Contribute to the growing industry of oligonucleotide (DNA-RNA) based therapeutics. Responsibilities may include but are not limited to: Technical lead for downstream processes and unit operations. Responsible for process modeling and consulted on process fit and throughput assessments. Responsible for process design review for large capital projects, including user requirements specifications development, P&IDs, layouts, and equipment selection. Responsible for equipment design and procurement support, including equipment and instrumentation specification/selection, equipment procurement, FAT/SAT, installation, commissioning, qualification, and turn-over to manufacturing. Consulted on Automation/Controls design, including instrumentation selection, equipment interface, and equipment module / phase design. Support Chemical Development in the development, characterization, and scaleup of innovative Oligonucleotide production processes and technologies. Responsible for Building Information Model (BIM) review for process piping and equipment, cleanroom design, and general spatial planning to achieve manufacturing requirements. Responsible for planning, review, and execution of process startup, commissioning, and qualification activities. Consulted on project management aspects including project schedule, budget, and coordination of multi-disciplinary teams. Support EHS activities including PHA, PSSR, and PSM compliance. Qualifications
REQUIRED
Bachelor's or Master's Degree in Chemical Engineering or equivalent education/experience . 8+ years of combined experience in pharma/biopharma and fine chemicals industry to include experience with P&IDs, facility layouts, mass and energy balances, solvent handling, equipment design, user requirement specifications (URS). 6+ years of experience with medium to large-sized projects through all phases, including design, design review, process hazard analysis, equipment procurement, installation, commissioning, and qualification.
DESIRED:
Familiarity with current
ASME BPE
sanitary piping and equipment design standards, electrical standards such as National Fire Protection Association / National Electrical Code (NFPA 70 / NEC), and International Fire and Building Code Experience with Oligonucleotide manufacturing downstream unit operations and processes including: Column packing, preparative liquid chromatography, buffer preparation, reaction, ultrafiltration, evaporation, drying. Experience with design of industrial control systems, including SCADA, PLCs, and BAS, and validation documentation, including installation, operational, and performance qualification (IQ/OQ/PQ) protocols. Experience and familiarity with OSHA Process Safety Management (PSM) program requirements. Engineering, communication, and organizational skills to support the safe, efficient, and compliant design, construction, and startup of an API manufacturing facility. Self-motivated, hands-on problem solver with the ability to work within multi-disciplinary teams, including process development, manufacturing, validation, quality, safety, and project management personnel. Additional Details This job has a full time weekly schedule. Applications for this job will be accepted until at least May 21, 2026 or until the job is no longer posted. The full-time equivalent pay range for this position is $124,160.00•$194,000.00/yr plus eligibility for bonus, stock and benefits. Our pay ranges are determined by role, level, and location. Within the range, individual pay is determined by work location and additional factors, including job-related skills, experience, and relevant education or training. During the hiring process, a recruiter can share more about the specific pay range for a preferred location. Pay and benefit information by country are available at: https://careers.agilent.com/locations Agilent Technologies, Inc. is an Equal Employment Opportunity and merit-based employer that values individuals of all backgrounds at all levels. All individuals, regardless of personal characteristics, are encouraged to apply. All qualified applicants will receive consideration for employment without regard to sex, pregnancy, race, religion or religious creed, color, gender, gender identity, gender expression, national origin, ancestry, physical or mental disability, medical condition, genetic information, marital status, registered domestic partner status, age, sexual orientation, military or veteran status, protected veteran status, or any other basis protected by federal, state, local law, ordinance, or regulation and will not be discriminated against on these bases. Agilent Technologies, Inc., is committed to creating and maintaining an inclusive in the workplace where everyone is welcome, and strives to support candidates with disabilities. If you have a disability and need assistance with any part of the application or interview process or have questions about workplace accessibility, please email job_posting@agilent.com or contact +1-262-754-5030. For more information about equal employment opportunity protections, please visit www.agilent.com/en/accessibility.
Travel Required:
Occasional Shift:
Day Duration:
No End Date Job Function:
Manufacturing Graduate and Student Career Site Visit our career site and learn more about Agilent Watch our video playlist to get a glimpse of life at Agilent! As a global leader in laboratory and clinical technologies, we are passionate about bringing great science to life. Our commitment to quality and innovation supports cutting-edge life science research, patient diagnostics, and ensures the safety of water, food, and pharmaceuticals. As scientists and clinicians pursue small, everyday advances and life-changing discoveries, we provide trusted answers to their most critical questions and challenges. Leveraging more than 50 years of expertise, we create advanced instruments, software, and consumables supported by teams of highly skilled and knowledgeable people. With 18,000 employees around the world, our global reach and comprehensive solutions provide the most reliable and accurate results, as well as optimal scientific, economic, and operational outcomes. We work collaboratively with our customers on their journey to make a real difference in human lives. Our culture is founded on trust, respect, and uncompromising integrity, and we pride ourselves on being a dynamic and inclusive workplace that celebrates diversity and fosters innovation. We can't wait for you to join us as we continue our mission to improve the world around us. Information about Agilent is available at Agilent.com.

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