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Lead System Engineer

Job

System One

Pittsburgh, PA (In Person)

Full-Time

Posted 1 week ago (Updated 5 days ago) • Actively hiring

Expires 6/3/2026

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Job Description

Title:
Lead Design Engineer Location:
Onsite, Pittsburgh, PA 15213
Type:
Direct-Hire/Permanent Hours:
Standard business hours
Start:
May Overview:
Join a cutting-edge lab to discover novel therapeutics that are seeking a highly motivated Lead Engineer to support the development, integration, and operation of advanced aerosol delivery, sensing, and exposure systems for human-relevant experimental platforms. This role focuses on ensuring precise, reproducible generation and delivery of airborne agents, as well as integration of instrumentation and multi-system platforms to enable controlled and standardized experimental workflows. The position will contribute to system optimization, performance validation, and operational readiness in complex laboratory environments.
Responsibilities:
Design, prototype, and refine biomedical devices and components supporting advanced experimental system Develop and optimize fabrication processes to ensure consistency, quality, and scalability Contribute to selection and evaluation of materials, fabrication methods, and assembly workflows Perform testing and validation of device performance, including durability, reproducibility, and functional integrity Collaborate with scientific and engineering teams to align device design with experimental requirements Maintain documentation related to design iterations, fabrication processes, and quality control Troubleshoot device-related issues and implement design improvements Support coordination of engineering activities across multidisciplinary teams and contribute to project execution Contribute to preparation of technical documentation, reports, and related materials
Requirements:
Bachelor's degree in Biomedical Engineering, Mechanical Engineering, Electrical / System Engineering, or a related field Minimum of 3 years of relevant experience in device design, prototyping, or fabrication Experience with engineering design tools (e.g., CAD software) Strong problem-solving skills and attention to detail Ability to work effectively in multidisciplinary research and engineering environments Preferred Qualifications Master's or Ph.D. in a relevant engineering discipline Experience with fabrication of small-scale or precision-engineered devices, including Organs-on-Chips, injection molding, and CNC milling Familiarity with polymer-based materials and manufacturing processes Experience with iterative prototyping and design-for-manufacturing principles Experience working at the interface of engineering and biological systems #M3 #LI-DS2
Ref:
#558-Scientific

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