Position:

IT Lead -

R D Informatics Location:

Newark, CA Job Id:

429 # of

Openings:

0 IT Lead -

R D Informatics Position Type:

Contract (9-months) About Us Protagonist Therapeutics is a biopharmaceutical company built on a proprietary peptide technology platform that has now produced two FDA-approved, first-in-class medicines, generating royalties and milestones from global commercial partnerships with Johnson and Johnson and Takeda Pharmaceutical Company Limited. ICOTYDE ™ (icotrokinra), licensed to Johnson & Johnson company Janssen Biotech, Inc., is the first and only targeted oral peptide that precisely blocks the Interleukin-23 receptor. ICOTYDE was launched in the U.S. in March 2026 for the treatment of moderate-to-severe plaque psoriasis in adults and pediatric patients 12 years of age or older and is in Phase 3 development for psoriatic arthritis, ulcerative colitis and Crohn's disease. ICOTYDE was jointly discovered by Protagonist and Johnson & Johnson scientists, with Protagonist having primary responsibility for the development of ICOTYDE through Phase 1, and Johnson & Johnson assuming responsibility for further clinical and regulatory development and commercialization. Protagonist also discovered and led research and development through Phase 3 for MIMRYLO ™ (rusfertide), a first-in-class hepcidin mimetic peptide licensed to Takeda Pharmaceutical Company Limited for worldwide commercialization. MIMRYLO is approved in the U.S. for the treatment of erythrocytosis in adults with PV. The Company also has a number of clinical and preclinical programs based on clinically and commercially validated targets and addressing unmet medical needs, including an oral IL-17 antagonist peptide, anti-obesity dual and triple agonists, an oral hepcidin functional mimetic, and the recently announced IL-4 and amylin discovery programs. More information on Protagonist, its pipeline drug candidates, and clinical studies can be found on the Company's website at https://www.protagonist-inc.com . Position Summary We are seeking a hands-on R D Informatics Lead to own and continuously improve Protagonist's R D Informatics capabilities supporting our lab functions. This role will serve as the business-facing IT system owner and technical lead for R D Informatics and Discovery lab systems, with primary ownership of Thermo Fisher Scientific - Labguru across ELN, SDMS, and LIMS capabilities. The successful candidate will partner closely with Discovery scientists, IT, Quality, lab operations, and external vendors to translate scientific workflows into scalable, secure, well-governed, and user-friendly digital research solutions. This role combines strategic roadmap ownership with practical system administration, configuration, support, implementation delivery, user enablement, data governance, integrations, reporting readiness, and AI/ML-ready scientific data foundations. The ideal candidate brings Discovery science domain understanding, R D Informatics ownership, Labguru expertise, technical delivery capability, and strong cross-functional stakeholder leadership. We are committed to a thriving in-office culture. This role requires being on-site at our office in Newark, CA 4 days a week. Key Responsibilities

• Serve as the primary R D Informatics lead, accountable for strategy, roadmap, implementation, administration, lifecycle management, and continuous improvement of Labguru and related lab informatics solutions (including AI/ML solutions).
• Lead R D lab transformation efforts by partnering with scientists, IT, Quality, lab operations, and vendors to convert current-state workflows into standardized, scalable, secure, and supportable digital processes.
• Own day-to-day support and maintenance of R D Informatics platforms, including Labguru user support, access management, configuration updates, issue triage, enhancement requests, release assessments, vendor escalations, and production readiness.
• Partners with scientists and lab operations functional leads in gathering and translating business and scientific requirements into scalable, well-engineered secured platform solutions.
• Act as product owner for R D Informatics capabilities by managing the roadmap, intake process, enhancement backlog, prioritization framework, stakeholder communication, and governance cadence.
• Serve as a consultative partner to scientists and research leaders to assess workflow pain points, define future-state processes, identify informatics opportunities, and recommend scalable digital solutions.
• Support integrations and interoperability across Labguru, laboratory instruments, automation tools, file/data transfer workflows, APIs or interfaces, scientific data repositories, reporting tools, and adjacent applications.
• Establish and maintain scientific data lifecycle and governance practices across data capture, traceability, reporting, archival, reuse, security, and AI/ML-ready research data foundations.
• Coordinate vendor activities, system upgrades, release assessments, issue resolution, enhancement requests, validation or testing support, change control inputs, and production readiness activities.
• Drive user enablement and adoption through training content, quick-reference materials, onboarding support, usage monitoring, feedback loops, adoption metrics, risk tracking, and executive-ready status updates. Required Qualifications
• Bachelor's degree in Computer Science, Information Systems, Life Sciences, Bioinformatics, Chemistry, Biology, Engineering, or a related field; equivalent relevant experience may be considered.
• 6-8+ years of hands-on R D and lab informatics experience supporting Discovery, biotechnology, pharmaceutical, or life sciences organizations.
• Direct hands-on experience implementing, configuring, administering, maintaining, and supporting Thermo Fisher Scientific Labguru or similar tools is required.
• Demonstrated experience acting as a system owner, platform lead, product owner, application administrator, or technical lead for R D Informatics platforms such as ELN, SDMS, LIMS, sample management, inventory, chromatography, reporting tools, or scientific data systems.
• Strong understanding of Discovery laboratory workflows, experiment documentation, sample tracking, inventory management, assay workflows, instrument-generated data, and scientific research data lifecycle needs.
• Experience translating scientific workflows into configured, tested, deployed, supportable, and well documented informatics solutions.
• Working knowledge of application data models, metadata, data migration, integrations, APIs or file-based interfaces, permissions, security controls, backup/recovery concepts, reporting enablement, and data governance practices.
• Strong analytical, problem-solving, documentation, communication, facilitation, vendor management, and stakeholder management skills. Preferred Qualifications
• Background in biology, chemistry, medicinal chemistry, molecular biology, bioinformatics, or a related Discovery science discipline, with progression into R D Informatics, IT systems, software implementation, platform ownership, or data engineering.
• Experience supporting additional R D Informatics or scientific platforms, including ELN, SDMS, chromatography data systems, LIMS, automation platforms, data lakes, scientific data warehouses, AI solutions or reporting tools.
• Experience with lab automation, instrument connectivity, structured data capture, and AI/ML-ready scientific data foundations.
• Familiarity with GxP considerations, data integrity expectations, audit trails, validation/testing practices, change control, compliant documentation, and regulated research or quality environments.
• Experience defining platform operating models, vendor roadmaps, release processes, enhancement backlogs, support tickets, SLA expectations, production support practices, and system governance forums.
• Ability to create executive-ready status updates, project plans, adoption metrics, risk logs, decision documents, business cases, and implementation roadmaps for R D Informatics or lab transformation initiatives.

Pay Range The base pay range for this position at commencement of employment is expected to be between $170,000 and $210,000/year; however, base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. Benefits A top priority for Protagonist Therapeutics, Inc. is to provide a robust and comprehensive health and wellness program for our employees and their families. We offer a variety of high-quality coverage and benefit options. Health Care benefits. Protagonist covers 100% of the premium cost for medical, dental, and vision coverage for all full-time employees and their dependents. Flexible Spending Accounts - Healthcare FSA, Dependent Care FSA, Commuter Benefits 401(k) Plan Flexible Vacation Policy Life Insurance (Basic, Voluntary & AD&D) Short Term & Long Term Disability Company paid lunch and snacks Apply for this Position