ROLE SUMMARY

You will serve as the hands-on, proactive, strategic leader responsible for advancing the application of Artificial Intelligence (AI) across the Clinical Development lifecycle. You will partner closely with the Oncology Clinical Development, Clinical Operations, Biostatistics, Data Science, Medical Affairs, Regulatory Affairs, and Digital organizations to identify, develop, and scale AI-driven capabilities that improve trial design, data review, study execution, operational efficiency, decision-making, and regulatory readiness. You will leverage your deep expertise in Clinical Development with your proven track record of delivering AI-enabled solutions in pharmaceutical research and development environments including your experience interacting with regulatory agencies on implementation of AI solutions in clinical development.

ROLE RESPONSIBILITIES

Strategic AI Leadership Develop and accountable to execute the enterprise strategy for AI-enabled Clinical Excellence across Clinical Development. Identify high-value opportunities to accelerate development timelines, improve quality, reduce operational burden, and enhance decision-making through AI. Serve as a trusted advisor to senior leaders on emerging AI capabilities, industry trends, and competitive advancements. Clinical Development Innovation Drive adoption of AI solutions across study design, protocol optimization, feasibility assessments, patient recruitment, trial execution, and clinical data review. Lead development of AI-enabled approaches to improve clinical trial performance, operational excellence, and portfolio decision-making. Enable predictive and prescriptive analytics to support program-level and study-level decisions. AI Product Development and Deployment Partner with digital, data science, and technology teams to design, build, validate, and deploy AI-powered tools and platforms. Establish frameworks for scalable AI solutions that integrate into existing clinical development workflows. Responsible for the development of agentic AI, generative AI, predictive analytics, and workflow automation solutions supporting clinical operations and development teams. Regulatory and Governance Leadership Provide subject matter expertise on global regulatory expectations for AI, machine learning, and advanced analytics within drug development. Partner with Regulatory Affairs and Quality organizations to establish AI governance frameworks, validation approaches, and risk management processes. Monitor evolving health authority guidance and industry standards related to AI-enabled development activities. Cross-Functional Leadership Build strong partnerships across the Oncology Clinical Development, Clinical Operations, Biostatistics, Regulatory Affairs, Medical, Safety, and Digital organizations. Lead multidisciplinary teams responsible for AI innovation initiatives. Drive organizational adoption through education, change management, and capability building. External Engagement Represent the organization in industry forums, consortiums, health authority interactions, and scientific conferences related to AI and Clinical Development innovation. Build relationships with key external partners, technology providers, and academic collaborators.

MINIMUM QUALIFICATIONS

MD and 4+ years of relevant experience within pharmaceutical, biotechnology, CRO, regulatory, or healthcare organizations OR PhD in Life Sciences, Clinical Research, Data Science, Biostatistics, Computer Science, Engineering, or related field and 5+ years of relevant experience within pharmaceutical, biotechnology, CRO, regulatory, or healthcare organizations OR MS in Life Sciences, Clinical Research, Data Science, Biostatistics, Computer Science, Engineering, or related field and 7+ years of relevant experience within pharmaceutical, biotechnology, CRO, regulatory, or healthcare organizations. Experience designing, developing, and implementing AI, machine learning, or advanced analytics solutions in clinical research settings. Experience supporting Clinical Development, Clinical Operations, Clinical Science, Clinical Data Review, or Regulatory Science activities. Experience leading cross-functional programs involving clinical, regulatory, scientific, and technical stakeholders. Strong understanding of GCP, clinical trial conduct, drug development processes, and regulatory requirements. Experience translating complex scientific or operational challenges into scalable technology-enabled solutions. Excellent communication and executive influencing skills.

PREFERRED QUALIFICATIONS

Expertise in Clinical Development, Oncology, Regulatory Science, Data Science, or Clinical Informatics. Experience developing and deploying Large Language Models (LLMs), Generative AI, Agentic AI systems, or workflow automation platforms in regulated environments. Experience in Oncology Familiarity with emerging regulatory frameworks governing AI-enabled drug development. Experience interacting with global regulatory agencies (e.g. FDA, EMA, MHRA, PMDA, Health Canada Experience leading enterprise AI transformation initiatives. Strong publication record and scientific credibility within clinical research and AI innovation. Experience building and leading high-performing teams. Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.

PHYSICAL/MENTAL REQUIREMENTS

None

NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS

Occasional travel may be required

WORK LOCATION ASSIGNMENT

This is a hybrid role requiring you to live within commuting distance and work on-site an average of 2.5 days per week. The annual base salary for this position ranges from $176,600.00 to $294,300.00. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 20.0% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States. This role is posted in multiple locations. If you are applying for the role in an secondary job posting location where pay transparency regulations apply, your Talent Advisor will share the local pay information with you during the first interview. Relocation assistance may be available based on business needs and/or eligibility. Candidates must be authorized to be employed in the U.S. by any employer. U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future. Sunshine Act Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative. EEO & Employment Eligibility Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States. Pfizer endeavors to make www.pfizer.com/careers accessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email disabilityrecruitment@pfizer.com. This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Requests for any other reason will not be returned. To learn more about acceptable and prohibited uses of AI during the recruitment process, please review our candidate AI-use guidelines available on Pfizer Careers. Information & Business Tech Apply Now\nActive Filters\nHead of AI Clinical Ex...\nCollegeville, PA\nClear All\nPowered By Cookie Policy We use cookies to improve your experience on our site. 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Head of AI Clinical Excellence