Scientist

Scientist at Hartmann Young Scientist at Hartmann Young in Allston, Massachusetts Posted in about 22 hours ago.

Type:

full-time

Job Description:

Manager, Translational Scientist | Cardiology Dallas, Texas, United States (Remote) Hartmann Young are partnering with a fast?growing, privately held biotech advancing a novel therapeutic platform in cardiovascular disease, with a strong focus on cardiomyopathy and heart failure. This is a high?impact Manager?level Translational Scientist role within a lean, agile organization, offering meaningful hands?on ownership across preclinical and early clinical development. The role is remote across the U.S., with Dallas / Plano-based candidates of particular interest given the company's growing presence in Texas. This is an urgent hire and an opportunity to join a program at a critical development inflection point. The Role You will contribute scientific leadership across translational cardiovascular research, bridging mechanistic biology, cardiovascular animal models, and early clinical development. The role is ideal for a translational biologist with strong in vivo cardiovascular expertise who can partner cross?functionally to support progression from preclinical studies into Phase 1/2 clinical trials. Key Responsibilities Lead and execute translational biology activities supporting cardiovascular programs from preclinical through early clinical stages Serve as a subject?matter expert in cardiovascular animal models, including models of cardiomyopathy and heart failure Design, oversee, and interpret nonclinical efficacy, PK/PD, and mechanistic studies Translate preclinical findings into clinical hypotheses, biomarker strategies, and dose rationale Collaborate closely with Clinical Development, Clinical Operations, Regulatory, and Biometrics to enable efficient bench?to?bedside translation Contribute to key program documents including nonclinical study reports, Investigator's Brochures, translational sections of protocols, and regulatory submissions Manage and interact with external CROs, academic collaborators, and vendors supporting in vivo and translational studies Support interpretation of emerging early clinical data in the context of preclinical and translational evidence Expertise We're Looking For PhD (or MD with strong research focus) in cardiovascular biology, physiology, pharmacology, or a related field Demonstrated experience in a translational biology or preclinical cardiovascular role within biotech, pharma, or an academic-industry environment Strong hands?on familiarity with cardiovascular animal models, particularly: Cardiomyopathy (genetic and acquired models) Heart failure-relevant models (HFrEF / HFpEF) Solid understanding of translational biomarkers, PK/PD relationships, and mechanistic data integration Experience supporting programs advancing toward or into early clinical development (Phase 1 / 2) Comfort operating in a fast?paced, resource?lean biotech environment Strong scientific writing, communication, and cross?functional collaboration skills Why Join? Join a mission?driven biotech focused on high?unmet?need cardiovascular diseases Hands?on translational role with real impact on program direction and clinical strategy High visibility within a flat organizational structure Remote U.S. working model, with added opportunity for local impact if Dallas?based Opportunity to contribute to programs with genuine potential to improve outcomes in heart failure and cardiomyopathy