The Division of Pulmonary, Critical Care and Sleep Medicine at the University of Maryland, Baltimore, School of Medicine is seeking ahighly motivated Postdoctoral Researcher to develop radiolabeled agents for molecular imaging and targeted radionuclide therapy, and tocarry out quantitative in vivo PET and SPECT imaging, biodistribution, and dosimetry studies supporting the preclinical and translationaldevelopment of these agents. Key Responsibilities Design, synthesize, and evaluate chelators, ligands, andradiolabeled conjugates for diagnostic and therapeutic radionuclides. Develop and optimize radiolabeling methods and assessradiochemical yield, purity, and complex stability under physiological conditions. Design and conduct small animal PET/SPECT/CTimaging studies, including image reconstruction, quantification, and kinetic analysis. Perform ex vivo biodistribution studies anddosimetry modeling to support dose selection and normal tissue safety assessment. Collaborate with protein engineering, syntheticbiology, and immunology colleagues on the design and evaluation of targeted agents. Contribute to translational and IND-enablingactivities, including method validation, quality control, and regulatory documentation. Present findings at internal meetings andscientific conferences, and prepare manuscripts for high-impact journals. Mentor junior researchers and contribute to acollaborative lab environment. Qualifications PhD in Radiochemistry, Medicinal or Inorganic Chemistry,Nuclear Medicine, Medical Physics, or a related field. Strong hands-on radiolabeling experience with diagnostic and/or therapeuticradionuclides, and formal radiation safety training. Proficiency in synthetic organic or coordination chemistry and in analyticalmethods including HPLC, radio-TLC, LC-MS, and NMR. Experience with chelate chemistry and bioconjugation strategies forradiometal-based agents. Experience with small animal

PET/SPECT

imaging, biodistribution studies, and dosimetry analysis isdesirable. Experience with alpha-emitting radionuclides or with GMP and IND-enabling work is a plus. Ability to workindependently and within a collaborative team; strong communication and writing skills.

Application:

Interestedcandidates should send their CV, a cover letter outlining their research experience, interest in this position and contact information forthree references to Dr. Nalinikanth Kotagiri at NKotagiri@som.umaryland.

edu Desired start date:

Immediately