Target PR Range:

39-40/hr •Depending on experience TheSkincare Aesthetics Bioprocess Innovation Center (SABIC) is located in North Chicago and is a joint effort between Skincare Aesthetics R D and Bioprocess Engineering R D towards bioprocess discovery related to SkinMedica's cell-based technologies for topical skincare. The incumbent will help develop and optimize protocols for 3D bioreactor cell culture work using a human adherant primary cell line coupled with microcarriers as well as more traditional 2D cell culture. This role will focus on bioprocess optimization and secretome characterization.

Responsibilities:

Conduct laboratory experimentation for cell culture and bioprocess development, optimization, and scale-up in a quest to innovate new cell-based active materials and processes. Stirred-tank bioreactor bioprocess development and optimization Support scale-up from 100 mL to 15+L cultures Evaluate and optimize feeding process, including continuous perfusion feed system Daily checks and maintenance through bioprocess experiments (like glucose/lactate monitoring, viability and proliferation tracking etc) Perform bioassays to characterize secretome product (like ELISA, flow cytometry, immunofluorescent imaging etc) Assist with sample prep and working with collaborators for secretome characterization Assist in analysis and interpretation of proteomic, lipidomic, and metabolomic data Regular updates through oral presentations and written technical reports Education and Experience Degree in Chemical Engineering, Bioengineering, Biology, or other relevant scientific discipline with BS and typically 5+ years of experience, MS and typically 2+ years of experience, or PhD and typically 0+ years of experience in industry Must have strong fundamentals in cell biology Must have hands-on experience with cell culture Desirable to have experience working with bioreactors, process optimization, and scale-up Proven ability to adjust accordingly in response to shifting priorities Proven ability to design and carry through multiple experiments in parallel