Department:

SOM KC Pharmacology, Toxicology and Therapeutics•

Ding Lab Position Title:

Postdoctoral Fellow•

Wen-Xing Ding Lab Job Family Group:

Professional Staff Job Description Summary:

Within this research program, the postdoc fellow will spearhead the studies on mitochondria dynamics and mtDNA-mediated innate immune response in chronic liver diseases in particular alcohol-associated liver disease and metabolic dysfunction associated steatotic liver disease. The study requires expertise in mitochondria and liver biology. The position will perform animal research (genetic animal mouse breeding, alcohol and high-fat diet feeding, IV and IP injection, oral gavage, tissue harvesting and cellular organelle isolation), biochemical and histological analysis, as well as omics data analysis and manuscript preparation. The Postdoc will work under the direct mentorship of principal investigator (PI) Wen-Xing Ding, PhD, Professor in the Department of Pharmacology, Toxicology, and Therapeutics (PTT). The research is housed in modern laboratory space with state-of-the-art equipment and will build on a long history of innovative service to the KUMC research community.

Job Description:

Key Roles and Responsibilities:

Participate in regular communication with the PI and colleagues via both group laboratory and one-on-one meetings. Maintain accurate and well-organized research records to ensure data integrity and accessibility. Spearhead the creative design, execution, and analysis of complementary in vitro experiments using mouse and human cells/tissues within a multidisciplinary team setting (e.g., primary mouse hepatocyte isolation and human liver tissue samples). Lead cause-effect experiments using mouse models within a team setting to define the in vivo impacts of mitochondria dynamics in liver biology. Collect, analyze, and interpret data for planning of future experiments, resultant publications, and grant applications. Work directly with the PI to prepare manuscripts for publication in scientific journals based on experimental results, as well as to write reviews on related topics. Work directly with the PI to prepare grant applications in support of both individual career development and team laboratory funding. Participate in the dissemination of results by presenting to both the scientific and general audiences from local to international forums. Co-mentor junior trainees in the research laboratory. Lead aspects of routine laboratory and animal model maintenance. More specifically, this includes working closely with the PI to coordinate the day-to-day management of laboratory operations, such as upholding personnel safety protocols, overseeing equipment and supply logistics, coordinating ongoing research initiatives, and ensuring adherence to regulatory standards. This job description is not designed to cover or contain a comprehensive listing of activities, duties or responsibilities that are required of the employee for this job. It is only a summary of the typical functions of the job, not an exhaustive list of all possible job responsibilities, tasks, duties, and assignments. Furthermore, job duties, responsibilities and activities may change at any time with or without notice.

Required Qualifications:

Education:

PhD or MD in biomedical sciences and liver research

Work Experience:

Research experience in a wet bench laboratory Mentorship experience of junior technicians and trainees within a laboratory setting This position requires a formal degree in the cited discipline area(s) to ensure that candidates have advanced knowledge, analytical skills and professional competencies necessary to perform the duties of the position. The level of degree is commonly recognized as the standard qualification for similar roles in the public and private sector, ensuring that the university remains competitive with industry aligned practices, enhances collaboration with external partners, and supports the delivery of services and programs that meet professional and market-driven expectations.

Preferred Qualifications:

Education:

PhD in

Toxicology Work Experience:

Technical background experience in molecular biology, cellular imaging and animal experimentation in liver diseases Experience in bioinformatics

Required Documents:

CV/Resume Cover Letter Comprehensive Benefits Package:

Coverage begins on day one for health, dental, and vision insurance and includes health expense accounts with generous employer contributions if the employee participates in a qualifying health plan. Employer-paid life insurance, long-term disability insurance, and various additional voluntary insurance plans are available. Paid time off, including vacation and sick, begins accruing upon hire, plus ten paid holidays. One paid discretionary day is available after six months of employment, and paid time off for bereavement, jury duty, military service, and parental leave is available after 12 months of employment. A retirement program with a generous employer contribution and additional voluntary retirement programs (457 or 403b) are available.

https:

//www.kumc.edu/human-resources/benefits.html

Employee Type:

Regular Time Type:

Full time

Rate Type:

Salary Compensation Statement:

The pay range listed for this position is determined by our compensation program using market data and salary benchmarking. A combination of factors is considered in making compensation decisions including, but not limited to, education, experience and training, qualifications relative to the requirements of the position, and funding. At the University of Kansas Medical Center, a reasonable estimate for the starting pay range will be the minimum to midpoint of the posted range, taking into account the combination of factors listed above.

Pay Range:

$63,480.00•$90,000.00 Minimum $63,480.00 Midpoint $76,739.00 Maximum $90,000.00 The mission of the University of Kansas Medical Center is to improve lives and communities in Kansas and beyond through innovation in education, research, and health care. The University of Kansas Medical Center is an Equal Opportunity/Affirmative Action employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, national origin, ethnicity, ancestry, age, protected veteran or disability status, marital status, parental status, or genetic information.

http:

//policy.ku.

edu/IOA/nondiscrimination https:

//kumc-publicpoliciesandprocedures.policystat.com/policy/8446235/latest/ Under Kansas state law, certain KUMC positions are subject to disability preference. For positions subject to this requirement, KUMC will offer an interview to a person who has applied for an open position who is qualified, with or without reasonable accommodation, to meet the performance standards of the position and who has presented acceptable proof of disability. If the position you apply for is subject to the disability preference requirement, you will be asked to provide information in support of your request for disability preference when you complete the application for employment.

https:

//civilrights.ku.

edu/annual-security-and-fire-safety-report https:

//www.e-verify.gov/sites/default/files/everify/posters/EVerifyParticipationPoster.

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Postdoctoral Fellow - Wen-Xing Ding Lab