Job Details ICR's Cancer Prevention science centers on developing preventive cancer vaccines. We are hiring a Principal Scientist with a deep background in peptide-based vaccine development, cancer immunology and immuno-oncology. As part of our mission to prevent age-related disease, training human immune systems to spot and destroy cancer before it becomes a problem is critical. We truly believe that an ounce of prevention is worth a pound of cure. With us, you'll get to: Lead ICR's Cancer Prevention Group in researching and developing novel preventive cancer vaccines Drive end-to-end design, execution and interpretation of preclinical vaccine studies, directly shaping the path to human translation Collaborate closely external KOLs and CRO partners to turn cutting-edge cancer immunology insights into first-in-class preventive vaccine programs Please apply if you have: A PhD, MD or both and at least 10 years of vaccine development experience, preferably cancer vaccines In-depth knowledge of and experience researching personalized cancer vaccines, including peptide-based vaccines and neoantigen-based cancer vaccines Extensive experience with vaccine epitope identification, selection/prioritization (of neoantigens), vaccine adjuvants and immune response monitoring Experience with molecular T cell receptor repertoire analysis and tracking, T cell proliferation assays, cytokine release assays and ELISPOT Experience deriving antigen-specific T cell clones and lines Expertise in cancer stem cell antigens, tumor-associated antigens, neoantigens, immuno-editing and immuno-monitoring Extensive knowledge of and experience with vaccine delivery systems, including peptide

• cell
• and viral-based systems The ability to work well with CROs and manage external projects Even if you don't meet all of these criteria, please apply anyway And you'll need: The ability to work in the United States without sponsorship To have an easygoing, hard-working personality Salary Starting base pay range: $165,000/yr
• $215,000/yr Starting additional compensation range: $7,500/yr
• $20,000/yr Starting position title and compensation are commensurate with experience.