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Job Function:

Discovery & Pre-Clinical/Clinical Development Job Sub Function:

Biotherapeutics R D Job Category:

Scientific/Technology All Job Posting Locations:

Malvern, Pennsylvania, United States of America, Spring House, Pennsylvania, United States of America Job Description:

About Innovative Medicine Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow. Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.

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//www.jnj.com/innovative-medicine We are searching for the best talent for a Senior Principal Scientist, Biologics Discovery Process Research (BDPR) Integrator - Protein Expression and Scale-Up to be located in Spring House, PA or Malvern, PA.

Purpose:

The Senior Principal Scientist, BDPR Integrator will serve as a cross-functional integrator within Biologics Discovery Process Research, connecting Discovery, Therapeutic Development & Supply (TDS), Chemistry, Manufacturing and Controls (CMC), and process development teams to advance biologics programs from discovery through early development. The role will provide integrative technical leadership grounded in mammalian expression, cell line development, and scale-up expertise, ensuring that expression feasibility, manufacturability, productivity, product quality, and scalable production considerations are incorporated into molecule selection, material supply planning, and program strategy. The preferred candidate is not only a deep technical expert in mammalian expression systems, stable cell line development, clone selection, and upstream process scale-up, but also an effective integrator who can translate technical data into development recommendations, align partners across functions, and proactively identify risks that could impact downstream development or CMC readiness.

You will be responsible for:

• Serving as the TDS scientific integrator on Discovery project teams, aligning strategy, data expect...