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10x Genomics

Scientist 1, Protein Assay Development, Spatial Biology

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Job Description

About the role: We are looking for an exceptional, multidisciplinary scientist to contribute to our product development efforts in our Spatial Biology department, developing technologies that map protein β€” and other biomolecules β€” directly within intact tissue. The ideal candidate will have a solid foundation in cell biology, immunology or tumor biology with strong troubleshooting skills and hands-on experience with tissue based imaging assays. This role will involve designing, running, and troubleshooting experiments to develop and optimize new assays in the area of spatial multiomics in tissues. You will collaborate closely with colleagues across chemistry, computational biology, software, engineering, and microfluidics to bring new products to life. We're looking for someone with strong analytical skills, curiosity about new technologies, and enthusiasm for working in a fast-paced, collaborative, multi-disciplinary environment.
What you will be doing:
Contribute to the optimization of tissue handling and processing protocols for protein staining, including FFPE samples, to improve antigen retention, staining consistency, and compatibility with high-plex imaging workflows. Design and execute experiments using novel imaging and biochemistry platforms integral to various spatial technology platforms under development at 10x Genomics. This includes in-depth analysis and reporting of your data through documentation and presentations to internal groups. Work closely with computational biologists and software engineers to interpret data generated by novel optical and biochemical assays.
Minimum Requirements:
PhD in Cell Biology, Immunology, Biochemistry or related field. 2+ years of hands-on experience in proteomics, in situ hybridization or other imaging based spatial techniques. Experience with tissue processing, histology, immunohistochemistry, cryosectioning, immunofluorescence including characterization by surface markers or gene expression. Experience working with antibodies, including mAb QC, conjugation and/or functional testing. Strong analytical background Strong organizational skills. Strong written and oral communication skills. Strong troubleshooting and problem solving skills. Ability to work in a fast-paced and quickly changing environment. Desire to build game-changing technologies and impact the world of life science research.
Preferred Skills and Experience:
Experience with multiplex protein assays is a plus Proficiency in R, Python, AI-aided coding or specialized omics data analysis software is a plus. Skills in image analysis are a plus. Below is the base pay range for this full-time position. The actual base pay will depend on several factors unique to each candidate, including one's skills, qualifications, and experience. At 10x, base pay is also just one component of the Company's total compensation package. This role is also eligible for 10x's equity grants, its comprehensive health and retirement benefit programs, and its annual bonus program or sales incentive program. During the hiring process, your 10x recruiter can share more about the Company's total compensation package. Pay Range $123,100β€”$166,500 USD Our teams are empowered and encouraged to follow their passions, pursue new ideas, and perform at their best in an inclusive and dynamic environment. We know that behind every scientific breakthrough, there is a deep infrastructure of talented people driving the life sciences industry and making it possible for scientists and clinicians to make new strides. We are dedicated to finding the very best person for every aspect of our work because the innovations and discoveries that we enable together will lead to better technologies, better treatments, and a better future. Find out how you can make a 10x difference. Individuals seeking employment at 10x Genomics are considered without regards to race, color, religion, national origin, age, sex, marital status, ancestry, physical or mental disability, veteran status, gender identity, or sexual orientation, or any other characteristic protected by applicable law. 10x does not accept unsolicited applicants submitted by third-party recruiters or agencies. Any resume or application submitted to 10x without a vendor agreement in place will be considered unsolicited and property of 10x, and 10x will not pay a placement fee. Please be aware of recruitment scams impersonating 10x Genomics. All recruiting communication will come from email addresses @ 10xgenomics.com . We also want to encourage you to apply to 10x Genomics positions directly on our careers site, https://careers.kula.ai/10xgenomics?pid=171812447059&domain=10xgenomics.com or from reputable third party sites, such as LinkedIn or Indeed. We will never request payment or sensitive personal information during the recruiting process. Apply for this position Autofill from resume Save time by uploading your resume. (Only PDF or DOCX format supported) Upload file Personal Information First name
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pdf & .docx, up to 20 MB Cover Letter Drag and drop files or click to upload Supported files: .pdf & .docx, up to 20 MB Equal Opportunity Employer Help us be an equal opportunity employer You are requested (but not required) to fill in the personal data below. This information is used solely for government reporting and will not influence our hiring decisions. Race or ethnicity Select... Gender Select... Self-identification of Veteran status (Completion is voluntary and will not subject you to adverse treatment) 10x Genomics is a Government contractor subject to the Section 4212 of the Vietnam Era Veterans's Readjustment Assistance Act of 1974, as amended by the Jobs for Veterans Act of 2002, which requires Government contractors to take affirmative action to employ and advance in employment: (1) Disabled veterans - A veteran who served on active duty in the U.S. military and is entitled to disability compensation (or who but for the receipt of military retired pay would be entitled to disability compensation) under laws administered by the Secretary of Veterans Affairs, or was discharged or released from active duty because of a service-connected disability; (2) Recently separated veteran - A veteran separated during the three-year period beginning on the date of the veteran's discharge or release from active duty in the U.S military, ground, naval, or air service; (3) Active duty wartime or campaign badge veteran - A veteran who served on active duty in the U.S. military during a war, or in a campaign or expedition for which a campaign badge was authorized under the laws administered by the Department of Defense; (4) Armed forces service medal veteran - A veteran who, while serving on active duty in the U.S. military ground, naval, or air service, participated in a United States military operation for which an Armed Forces service medal was awarded pursuant to Executive Order 12985 (61 Fed. Reg. 1209). If you believe that you belong to any of the categories of protected veterans, please indicate by making the appropriate selection. Veteran Status Select...
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According to the Paperwork Reduction Act of 1995 no persons are required to respond to a collection of information unless such collection displays a valid OMB control number. This survey should take about 5 minutes to complete. 10x Genomics does not discriminate on the basis of race, sex, color, religion, age, national origin, marital status, disability, veteran status, genetic information, sexual orientation, gender identity or any other reason prohibited by law in provision of employment opportunities and benefits. Apply for this position

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