Job Description

Scientist I

•CMC /

Protein Purification Contract:

South San Francisco, California, US Salary Range:

59.00

•65.00 |

Per Hour Job Code:

372046

End Date:

2026-10-31

Days Left:

29 days, 7 hours left Hi there, I'm Siddhi, Talent Expert with Collabera LLC. Hope this message finds you well! We're actively hiring for top performers, and I think you could be a great fit. Why apply now? Positions are filling fast, and we're hiring immediately. If this resonates with you, I'd love to chat about how your background aligns with this opportunity. Let's explore if it's the right next move for you. Ready to connect?

Email:

siddhi.kadakia@collabera.com or

Phone:

(847

•440-1112

Position Details:

Client Industry:

Pharmaceutical/Medical Device/Biotechnology

Title:

Scientist I

•CMC / Protein Purification

Location:

South San Francisco, CA 94080

Duration:

6 months ++ possibility of extension based on performance and business needs

Shift:

USA Standard Business Hours Shift

Pay Rate:

$59.00

•$65.00 per hour

Job Details:

What are the top 3-5 skills, experience or education required for this position:

BS with 5-7 years, or MS with 2-5 years; degree in Chemical Engineering, Chemistry, Biochemistry or related discipline

Hands on experience with mAb purification unit operations, including Affinity/IEX/HIC chromatography, nanofiltration, ultrafiltration/diafiltration, preferably with scale-up or GMP manufacturing; experience with scale-up equipment such as AKTA Ready/Process, single use mixers, TFF skids

Experience authoring standard operating procedures (SOPs) and reports, and maintaining well-documented records in an Electronic Lab Notebook

The Biologics CMC Development team has a long and rich history of biologics development.

Now located in a new state of the art facility in South San Francisco, the team leverages its comprehensive end-to-end CMC capabilities to work collaboratively through all phases of CMC development with a primary focus on advancing complex biologic therapies, such as bi-specifics and novel modalities, to human clinical studies and eventual licensure.

This Scientist I role is within a team of highly experienced scientists and managers who have directly enabled the development/IND submissions of 20+ novel oncology drugs and successfully filed two BLAs.

This position is an onsite role in a lab-based function.

To be successful candidates must enjoy and thrive in an onsite, highly collaborative lab environment with daily face-to-face cross-functional interactions between scientists.

Responsibilities include:

Scale-up protein purification processes, including Affinity/IEX/HIC/MM chromatography, nanofiltration, depth filtration and ultrafiltration/diafiltration

Large scale buffer preparation to support scale-up processes

Operate, troubleshoot, and maintain pilot-scale bioprocess equipment such as depth filtration systems, chromatography skids, virus filtration systems, TFF skids, mixers, tanks, pumps, and single-use assemblies

Perform pre-run readiness activities, including equipment setup, column packing/qualification, buffer/media verification, and raw material staging

Support incoming transfer processes to scale-up lab to support GLP toxicology study material production and outgoing transfer processes to GMP manufacturing site for clinical material production

Work efficiently, collaboratively, and cross-functionally toward project timelines and goals

Author standard operating procedures (SOPs), technical reports and maintain well-documented records in an electronic lab notebook (ELN)

Author and deliver technical presentations

Qualifications

Bachelor's Degree or equivalent education and typically 5 years of experience and MS or equivalent education and typically 2 years of experience

Must have CMC protein purification development experience with standard bioprocess unit operations such as chromatography separations (resin/membrane: affinity, CEX, AEX, HIC, MM) and filtration operations (depth filtration, virus filtration, sterile filtration, TFF)

Must have excellent attention to detail and ability to keep detailed written records

Demonstrated ability to independently design, execute and interpret critical experiments to answer scientific questions

Demonstrated ability to learn, understand and master new experimental techniques

Able to work collaboratively within and outside of the group

Able to author technical reports and presentations

Has understanding of biochemistry and bioprocess engineering concepts

Has strong planning and analytical skills

Experience with AKTA chromatographic instruments (such as AKTA Ready, AKTA process, AKTA Avant, AKTA Purifier, AKTA Pure or similar), TFF skids (such as Sartoflow 1000 or similar)

Demonstrated scientific writing skills and strong verbal communication skills including scientific data presentations

Has proficiency with MS Office software, ability to learn new software applications

Preferred:

Has hands on experience with executing antibody or antibody-like molecule purification techniques including resin chromatography (affinity, CEX, AEX, MMC), depth filtration, virus filtration, membrane chromatography, and TFF operations, preferably at pilot or GMP scale

Has hands on experience with unit operation development including cell culture harvest, affinity chromatography, polishing chromatography, virus filtration and ultrafiltration/diafiltration.

Understanding of analytical techniques, such as HPLC, LAL, and ELISA

Has hands on experience with high-throughput technologies and automation

Benefits:

The Company offers the following benefits for this position, subject to applicable eligibility requirements: medical insurance, dental insurance, vision insurance, 401(k) retirement plan, life insurance, long-term disability insurance, short-term disability insurance, paid parking/public transportation, (paid time , paid sick and safe time , hours of paid vacation time, weeks of paid parental leave, paid holidays annually

•These all are subject to applicable eligibility).

Job Requirement

mAb Protein Purification

Affinity Chromatography

IEX Chromatography

CEX/AEX Chromatography

HIC Chromatography

Mixed-Mode Chromatography

Nanofiltration

Depth Filtration

Virus Filtration

Sterile Filtration

Ultrafiltration/Diafiltration (UF/DF)

TFF

AKTA Ready/Process/Avant/Purifier/Pure

Pilot-Scale Bioprocess Equipment

Scale-Up

GMP Manufacturing

Buffer Preparation

Column Packing & Qualification

Bioprocess Development

CMC Development

SOP Authoring

Technical Reports

Electronic Lab Notebook (ELN)

Experimental Design

Troubleshooting

Process Transfer

GLP/GMP

HPLC

LAL

ELISA

Scientific Writing

Technical Presentations

Biochemistry

Bioprocess Engineering

Data Analysis

Cross-Functional Collaboration

Reach Out to a Recruiter

Recruiter

Email

Phone

Siddhi Kadakia

siddhi.kadakia@collabera.com