Houston, Texas 77092 Full-Time | W-2

Schedule:

Monday-Friday, 9:00 a.m.-5:00 p.m.

Pay:

$90-160k, depending on experience About the Job Gold Standard Analytics is hiring an Analytical Chemist to join our growing analytical testing laboratory in Houston, Texas. This is a hands-on laboratory position focused on high-throughput analytical testing, sample preparation, chromatography, mass spectrometry, method development, instrument maintenance, data review, and Certificate of Analysis generation . Our laboratory works with a wide variety of products and matrices, including: Peptides and research compounds Small molecules and active ingredients SARMs and related compounds Pharmaceutical and API materials Dietary supplements Kratom and botanical products Cosmetics and skincare products Raw materials Water and environmental samples Samples requiring elemental and heavy-metal analysis The successful candidate should be comfortable working independently around sophisticated analytical instrumentation and should understand that commercial laboratory testing requires much more than simply loading samples onto an instrument. Accuracy, documentation, repeatability, traceability, throughput, instrument uptime, and defensible analytical results are all critical parts of the position. Gold Standard Analytics operates an ISO/IEC 17025-aligned quality system and is working toward accreditation . This position will have the opportunity to directly contribute to laboratory procedures, method development, validation, automation, quality systems, and continued expansion of the laboratory's testing capabilities. Instrumentation Candidates with experience on any comparable analytical platform are encouraged to apply, although experience with Agilent Technologies equipment is especially valuable. Gold Standard Analytics utilizes analytical platforms including: Agilent 1290 Infinity II HPLC Agilent Triple Quadrupole

LC-MS/MS

Agilent 7850 ICP-MS Agilent autosampler systems MassHunter software OpenLab / Agilent analytical software ecosystem Related laboratory preparation, sample-handling and data-processing equipment Experience with Agilent, SCIEX, Thermo Scientific, Waters, Shimadzu or comparable instrumentation is acceptable. Primary ResponsibilitiesHigh-Throughput Analytical Testing Prepare, analyze and process analytical samples using HPLC, LC-MS/MS, ICP-MS and related analytical techniques. Prepare peptide, small-molecule, pharmaceutical, supplement, botanical, environmental and other sample types. Accurately perform weighing, dilution, extraction, filtration, centrifugation and other sample-preparation procedures. Prepare mobile phases, reagents, rinse solutions, standards, calibration solutions, internal standards, blanks, controls and QC samples. Follow laboratory worksheets, SOPs, analytical methods, sample queues and testing priorities. Process multiple samples and batches simultaneously while maintaining sample identity and traceability. Monitor turnaround times and immediately communicate issues that could delay testing. Recognize questionable results, failed controls, preparation errors or instrument problems before results are released. Maintain strict contamination-prevention practices. The source listing similarly treats practical preparation, batch processing and recognition of failed controls or instrument problems as core production-laboratory responsibilities. HPLC & Chromatography Operate HPLC systems for purity, potency, assay and related analytical testing. Review chromatograms and perform scientifically defensible integrations.

Evaluate:

Retention time Peak shape Resolution Baseline quality System suitability Calibration curves Carryover Replicate agreement Standards and blanks Identify coelution, contamination, matrix interference and questionable integrations. Reprocess analytical data only when technically justified and properly documented. Assist with development and optimization of HPLC methods for new compounds. Maintain HPLC columns and document column usage and performance.

LC-MS/MS

& Mass Spectrometry Operate triple-quadrupole

LC-MS/MS

systems for identity, confirmation, quantitation and related analyses. Review chromatographic and mass-spectral data. Develop and optimize acquisition methods where appropriate. Evaluate precursor/product ions, transitions, retention time and response. Assist with optimization of source conditions and analytical parameters. Recognize ion suppression, matrix effects, contamination and other causes of poor analytical performance. Perform routine source cleaning and maintenance. Help develop workflows for new analytes and testing categories. ICP-MS & Elemental Analysis Operate ICP-MS for elemental and heavy-metal analysis. Prepare standards, internal standards, blanks, QC materials and sample dilutions. Review calibration curves and QC recoveries. Monitor background, sensitivity, internal-standard response and instrument performance. Assist in identifying and addressing spectral and non-spectral interference. Perform routine maintenance including inspection and servicing of sample-introduction components. Maintain appropriate documentation for instrument performance, calibration and maintenance. Agilent guidance specifically identifies pump tubing, nebulizers, spray chambers, cones, lenses, rough pumps and cell-gas systems as routine ICP-MS maintenance areas, making hands-on maintenance competency particularly relevant to this position. Data Review & Certificate of Analysis Preparation The Analytical Chemist will be responsible not only for generating data but also for helping ensure that the data can be technically defended.

Responsibilities include:

Review chromatograms, spectra and quantitative results. Verify calibration calculations. Confirm QC acceptance. Investigate unexpected or inconsistent results. Compare replicates where applicable. Review standards, blanks and controls. Document deviations or unusual observations. Maintain traceability from sample receipt through final result. Prepare technically complete analytical data packages. Assist with preparation and technical review of Certificates of Analysis (COAs) . Ensure results entered into the laboratory system accurately match the analytical source data. Never alter, omit or manipulate analytical results for the purpose of obtaining a preferred outcome. The reference job description places similar emphasis on defensible integrations, calibration review, technical data packages and COA preparation. Method Development & Validation Gold Standard Analytics is rapidly expanding its analytical capabilities. The selected chemist will be expected to assist with: Development of methods for new analytes. Method transfer. Method verification. Method optimization. Method validation. Calibration-range development. Accuracy and precision studies. Specificity/selectivity evaluation. Carryover evaluation. Repeatability studies. Recovery experiments. Matrix-spike studies. Limit-of-detection and limit-of-quantitation work where applicable. Robustness studies. Preparation of method-development and validation documentation. Candidates who enjoy solving analytical problems and developing methods rather than simply following existing methods are especially encouraged to apply. Quality System & ISO/IEC 17025 The chemist will participate in the development and maintenance of Gold Standard Analytics' quality system.

Responsibilities may include:

Following approved SOPs and analytical methods. Creating and revising SOPs. Maintaining controlled laboratory records. Maintaining instrument maintenance and calibration records. Supporting training and competency records. Documenting deviations and nonconforming work. Performing root-cause investigations. Supporting corrective and preventive actions. Participating in proficiency testing. Supporting internal audits. Supporting method verification and validation. Maintaining complete traceability of analytical activities. Helping prepare the laboratory for

ISO/IEC 17025

accreditation. The comparison listing similarly includes SOP work, proficiency testing, QC investigations, corrective actions, audit preparation and records sufficient to reconstruct laboratory work. Instrument Maintenance & Troubleshooting This is a hands-on laboratory position. Candidates should be comfortable learning to perform routine maintenance rather than relying on vendor service for every issue.

Responsibilities include:

Mobile-phase preparation HPLC column installation and replacement LC-MS source cleaning ICP-MS sample-introduction maintenance Pump tubing replacement Nebulizer inspection and cleaning Torch inspection and replacement Cone inspection and cleaning Autosampler maintenance Tubing replacement Leak troubleshooting System flushing Instrument tuning Calibration Preventive maintenance Consumables monitoring Basic diagnostic troubleshooting Candidates should be able to recognize: Declining sensitivity Increasing background Carryover Pressure abnormalities Leaks Poor peak shape Retention-time shifts Contamination Failed system suitability Unstable signals Abnormal calibration behavior Routine maintenance is a meaningful part of keeping analytical systems productive; for example, Agilent's ICP-MS guidance calls for daily checks of pump tubing and nebulizers and periodic cleaning of cones, lenses, sample lines, pumps and the chiller system. Laboratory Operations The Analytical Chemist may also assist with: Sample intake Sample labeling Chain-of-custody documentation Sample storage Inventory Reference standards Reagents Solvents Columns Consumables Gas inventory Waste management Laboratory organization Equipment qualification Instrument logs Laboratory cleaning Sample retention and disposal Commercial analytical laboratories require documented sample identity and custody from receipt through testing and disposition; the sample-submission example you supplied includes sample IDs, requested tests, receipt condition, shipping information and sample-disposition instructions. Laboratory Automation Gold Standard Analytics is actively building automated laboratory workflows. Candidates interested in laboratory software, LIMS systems, instrument integration and AI-assisted laboratory automation will have opportunities to participate in projects involving: LIMS development Instrument-to-LIMS data transfer MassHunter integration OpenLab integration Automated sample queues Automated calculations Automated QC review Automated COA generation Barcode and sample-tracking systems Electronic chain of custody Automated method selection Laboratory data integrity Workflow optimization Programming experience is not required , but an interest in laboratory automation is highly desirable.

Required Qualifications Applicants should have:

Hands-on analytical laboratory experience. Experience with at least one instrumental technique such as:

HPLC UHPLC LC-MS LC-MS/MS ICP-MS GC GC-MS

Comparable analytical instrumentation Working understanding of sample preparation. Experience preparing standards, blanks and calibration solutions. Understanding of dilutions and quantitative calculations. Knowledge of contamination-prevention practices. Ability to interpret chromatographic or mass-spectrometric data. Strong attention to detail. Strong documentation practices. Ability to follow SOPs. Ability to troubleshoot laboratory problems. Ability to work independently. Ability to manage multiple samples and priorities simultaneously. A degree in one of the following is strongly preferred: Chemistry Analytical Chemistry Biochemistry Pharmaceutical Science Chemical Science Environmental Science Related scientific discipline Equivalent directly relevant laboratory experience may be considered. Preferred Qualifications Preference may be given to applicants with experience in one or more of the following: Agilent 1290 Infinity II Agilent

HPLC/UHPLC

Triple-quadrupole

LC-MS/MS

Agilent ICP-MS Agilent 7850 MassHunter OpenLab HPLC method development

LC-MS/MS

method development ICP-MS method development Peptide analysis Small-molecule analysis Pharmaceutical testing Research chemical testing Dietary supplements Botanical testing Heavy-metal analysis Commercial contract laboratories High-throughput analytical laboratories

ISO/IEC 17025 GMP GLP

Method validation Laboratory automation or LIMS software The original listing likewise makes hands-on industry experience substantially more important than academic coursework alone and gives preference to candidates familiar with commercial laboratory environments, chromatography/mass spectrometry software, method validation and routine troubleshooting. What We Are Looking For We are looking for someone who: Takes ownership of their work. Cares about producing accurate and defensible data. Does not hide mistakes. Documents problems when they occur. Understands that failed QC must be investigated rather than ignored. Can follow an established procedure but also recognize when something does not make scientific sense. Keeps instruments, benches and work areas organized. Can learn new methods quickly. Is comfortable in a fast-moving laboratory. Communicates problems early. Is interested in helping build a rapidly growing analytical laboratory. Compensation $90-160k per year , depending on: Relevant laboratory experience HPLC experience

LC-MS/MS

experience ICP-MS experience Agilent instrumentation experience MassHunter/OpenLab experience Method-development experience Ability to independently troubleshoot instruments Experience in commercial analytical testing Employment type: Full-time, W-2

Schedule:

Monday-Friday, 9:00 a.m.-5:00 p.m. How to Apply Please submit your resume and a short cover letter . In your cover letter, address the following: What analytical instruments have you personally operated? Which manufacturers and instrument models have you used? Which analytical software platforms have you used? What analytes or sample matrices have you personally tested? Describe your HPLC experience. Describe your LC-MS or

LC-MS/MS

experience. Describe your ICP-MS experience, if applicable. Have you developed or modified an analytical method? Have you reviewed chromatograms or mass spectra and performed integrations? Describe a difficult instrument, method, QC or data-quality problem you personally helped solve. Describe your experience working in a commercial, pharmaceutical, environmental, food, supplement, research or contract-testing laboratory. Describe any ISO/IEC 17025, GMP, GLP or other quality-system experience you have. Applications should clearly distinguish equipment you personally operated from equipment you merely observed or learned about academically.

Pay:

$90,000.00 - $170,000.00 per year

Benefits:

401(k) 401(k) matching Dental insurance Employee discount Flexible schedule Health insurance Life insurance Paid time off Vision insurance People with a criminal record are encouraged to apply Application Question(s): Hello, we are requiring prior experience with HPLC, LC-MS, ICP-MS and method development. If so please apply. If you have no experience or do not know what we are asking, then this job is not for you. Ability to

Commute:

Houston, TX 77092 (Preferred)

Work Location:

In person