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ALLIANCE CLINICAL LLC

Principal Investigator (MD/DO)

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What they do

A Clinical Investigator works on a clinical trial, and is responsible for ensuring that an investigation is conducted according to the signed investigator statement, the investigational plan, and applicable regulations; for protecting the rights, safety, and welfare of subjects under the investigator's care; and for the control of drugs under investigation. The Clinical Investigator must also meet requirements set forth by the FDA, EMA or other regulatory body. The qualifications must be outlined in a current resume and readily available for auditors.

$171,041 / year median in Florida

+8% projected growth

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Job Description

Internal Medicine Physician — Principal Investigator (Training Provided) Alliance Clinical Network — New Port Richey, FL | Part-Time | 1099 Independent Contractor About Alliance Clinical Network At Alliance Clinical Network, we advance medical innovation through high-quality, patient-centered clinical research. Our culture values compassion, integrity, and operational excellence—so you can focus on great medicine at a sustainable pace. Role Summary We're seeking an Internal Medicine physician (MD/DO) to serve as a Principal Investigator (PI) at our New Port Richey research site. This position is ideal for a physician seeking a slower pace of work and very flexible, part-time hours (approximately 10 hours/week). Comprehensive PI onboarding and ongoing support are provided. You'll provide medical oversight for clinical trials, ensure participant safety, and help generate high-quality data—without the heavy demands of a traditional clinic schedule. Key Responsibilities Serve as the study physician for assigned trials; ensure participant safety and ethical conduct. Review and confirm participant eligibility; oversee screening outcomes, AEs/SAEs, and retention trends. Perform/oversee study-specific medical assessments (histories/physicals, concomitant meds, endpoint review). Provide medical oversight to site staff (Sub-Investigators, CRCs, RNs, lab staff); be available for consults and safety questions. Collaborate with IRBs, sponsors, and CROs; join SIVs, monitoring visits, and close-out activities as needed. Ensure compliance with protocols, site SOPs, ICH-GCP, FDA/21 CFR, and Arizona state requirements. Review clinical data (labs, ECGs, vitals) and support timely safety reporting and documentation. Contribute to high-quality source documentation, query resolution, and continuous improvement of site processes. Why This Role Fits a Slower Pace Predictable scheduling anchored to study visit calendars (no overnight call; rare urgent escalations). Focused patient interactions with pre-screened volunteers and comprehensive study protocols. Dedicated research team handles day-to-day coordination; you provide clinical oversight and judgment. Flexible hours—work blocks can often be scheduled around your availability. Training & Support Structured PI onboarding (GCP/ICH training, protocol-specific training, mentorship from experienced PIs). Ongoing support from seasoned clinical operations, regulatory, and QA teams. Clear SOPs, templates, and documentation workflows to simplify your transition into research. Qualifications — Required MD or DO (Internal Medicine). Active, unrestricted Florida medical license. Interest in clinical research and comfort reviewing structured clinical data. Strong documentation, communication, and confidentiality practices (HIPAA/PHI). Qualifications — Preferred Prior experience as a PI or Sub-Investigator (not required—training provided for the right candidate). Familiarity with ICH-GCP and FDA regulations (21 CFR Parts 50, 54, 56, 312, 812). Board certification in Internal Medicine; DEA registration if required by specific protocols. Location On-site at New Port Richey, FL (some remote chart review/sponsor calls as studies permit). EEO Statement Alliance Clinical Network is an Equal Opportunity Employer/Contracting Partner. We celebrate diversity and are committed to an inclusive environment for all clinicians and staff. Accessibility/Accommodation If you require a reasonable accommodation to apply or interview, please let us know. ACN does not provide visa sponsorship for this role. Candidates who will require immigration or visa sponsorship at any time now or in the future (including, but not limited to, H‑1B, TN, or
STEM OPT
training plans) are not eligible for this role. About the
Company:
At Alliance Clinical Network, our mission is to advance medical research by enrolling diverse populations in high-quality clinical trials. We are committed to maintaining the highest standards of integrity and excellence, and to ensuring that every participant receives respectful and compassionate care. We strive to build a tightly knit, supportive and collaborative environment where our team members can thrive and make meaningful contributions to human health.

Benefits

  • Flexible Work Schedules