Clinical Trial Manager, CKDSouth San Francisco, CA Employer Maze Therapeutics Location South San Francisco, CA Start date Aug 27, 2026 View more categories View less categories Discipline Clinical , Clinical Research , Clinical Trials Required Education Bachelors Degree Position Type Full time Hotbed Biotech Bay Apply now Save job Click to add the job to your shortlist You need to sign in or create an account to save a job. Send job Job Details Company Job Details The Opportunity At Maze Therapeutics, we believe that precision medicine has the power to transform the lives of patients with both common and rare diseases. As a Clinical Trial Manager (CTM) at Maze Therapeutics, you'll play a hands-on role in co-leading and driving the execution of our Chronic Kidney Disease (CKD) clinical trials. You'll have the opportunity to contribute to mid to late-stage clinical studies, work cross-functionally with internal teams and external partners, and ensure trials run efficiently and with the highest quality standards. If you enjoy rolling up your sleeves, collaborating across teams, and bringing innovative medicines to patients, this role could be the perfect fit for you. The Impact You'll Have Steer the execution of one or more of our Phase 2 CKD clinical trials; from protocol development to achievement of corporate and study milestones such as first patient in, interim analysis, database lock, and study report completion. Manage external vendors including CROs, additional key vendors, and global investigative sites. Ensure adherence to study protocols, SOPs, ICH GCP guidelines by overseeing monitoring activities at investigative sites. Coordinate the development of study materials such as CRFs, ICFs, patient diaries. Act as the voice of Clinical Operations on cross-functional teams, including the Study Execution Team (SET). Partner with Clinical Operations and Clinical Science Team to engage with therapeutic area KOLs and Investigators. What We're Looking For A degree in a scientific discipline or health related field. Minimum of 4 years clinical research experience, including 2 years as a Clinical Trial Manager at a biopharmaceutical company or CRO. Experience with planning and executing Phase I-II trials is preferred. Demonstrated proficiency in implementing, monitoring, and management of clinical trials, from start-up to close-out. General knowledge of FDA regulatory requirements and ICH GCP guidelines. Strong organizational skills, ability to prioritize and multi-task. Excellent verbal and written communication skills. Demonstrated problem-solving and negotiation abilities. Ability to work as part of a team and build strong working relationships with internal and external partners. Capacity to roll-up sleeves to perform a broad range of clinical trial related tasks as needed. Willingness to travel as necessary, consistent with project needs. Excellent computer proficiency (Microsoft Office Suite, Project, Word, Excel, PowerPoint, Outlook). Experience with clinical trial databases (e.g., Medidata Rave, Veeva, etc.). About Maze Therapeutics Maze Therapeutics is a clinical-stage biopharmaceutical company harnessing human genetics to develop precision medicines for patients with kidney and metabolic diseases. Our clinical pipeline is anchored by two small molecule programs: MZE829, an APOL1 inhibitor for patients with APOL1‑mediated kidney disease, and MZE782, which targets genetic drivers of disease in phenylketonuria (PKU) and chronic kidney disease. We are also advancing a preclinical pipeline through our Compass platform, which links human genetic variants to the biological pathways that drive disease. Our People Maze is comprised of a team of passionate and creative professionals committed to discovering and delivering transformative medicines to patients suffering from both rare and common genetic diseases. We are fostering a culture that encourages vision, initiative and the development of talent. Our supportive work environment inspires creative thinking and freedom of expression, resulting in a stimulating atmosphere where people enjoy coming to work. While we have a passion for advanced science and pride ourselves on excellence in execution, ultimately, everything we do is about patients. Our Core Values Further Together

• Our path is paved with challenges, but with resilience and a team-first mentality, we'll achieve our mission. Impact Obsessed
• We embrace the bold, take calculated risks, and learn from our mistakes to improve the lives of others. Stand True
• Our integrity is foundational; it guides us no matter the obstacle. The expected annual salary range for employees located in the San Francisco Bay Area is $143,000
• $175,000.

Additionally, this position is eligible for an annual performance bonus. Maze performs position-based compensation benchmarking to industry market data to ensure we pay competitive wages. Determination of starting salary will depend upon a variety of job-related factors, which may include professional experience, skills, and job location. The expected salary range for this role may be modified in the future. Maze offers a robust benefits package to our eligible employees including competitive medical, dental, and vision insurance, mental health offerings, equity incentive plan, 401(k) program with employer match and a generous holiday and PTO policy. #LI-Hybrid Company About Maze Maze Therapeutics is a clinical-stage biopharmaceutical company harnessing the power of human genetics to develop novel, small molecule precision medicines for patients living with renal, cardiovascular and related metabolic diseases, including obesity. We are advancing a pipeline using our Compass platform, which allows us to identify and characterize genetic variants in disease and then link those variants to the biological pathways that drive disease in specific patient groups through a process we refer to as variant functionalization. Our Compass platform has been purpose-built to inform all phases of our drug discovery and development process through clinical trial design. We are currently advancing two wholly owned lead programs, MZE829 and MZE782, each of which represents a novel precision medicine-based approach for chronic kidney disease, or CKD. Our goal is to bring novel precision medicines to patients with common diseases, which is where we believe we can maximize our impact on human health. Our People Maze is comprised of a team of passionate and creative professionals committed to discovering and delivering transformative medicines to patients suffering from both rare and common genetic diseases. We are fostering a culture that encourages vision, initiative and the development of talent. Our supportive work environment inspires creative thinking and freedom of expression, resulting in a stimulating atmosphere where people enjoy coming to work. While we have a passion for advanced science and pride ourselves on excellence in execution, ultimately, everything we do is about patients. Our Core Values Further Together

• Our path is paved with challenges, but with resilience and a team-first mentality, we'll achieve our mission. Impact Obsessed
• We embrace the bold, take calculated risks, and learn from our mistakes to improve the lives of others. Stand True
• Our integrity is foundational; it guides us no matter the obstacle.

Company info Website https:

//mazetx.com/ Location 171 Oyster Point Blvd, Suite 300 South San Francisco

CA 94080

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