Technical Proficiency Full Job Description Description:

JOB OVERVIEW

The Remote Certifying Scientist will support the on-site Confirmation team in Newport, KY. This role is responsible for the quantitation of MS data, the final review of patient data and patient reports, and interacting with clients to assist with report issues, such as issuing new reports, updating patient demographic information, and similar concerns. Ethos manages clinical samples for diagnostic drug and metabolite confirmation analysis, and this candidate will engage in professional work in conducting toxicological examinations to identify and quantify target compounds. In addition, they will participate in validation studies, proficiency testing programs, method development, and other programs at the direction of the Confirmation Supervisor.

ESSENTIAL FUNCTIONS

Communicate with on-site team and Supervisor through electronic methods (email, instant messaging, shared documents, etc.) Final review and certification of patient reports following established protocols•specifically for urine and oral fluid testing•utilizing and reporting point of care testing, EIA screening, and

LC-MS/MS

confirmation testing results Transcribe data from first review onto final review list Review reports individually, checking for completion of all demographic information, all ordered tests, and that results correspond to established norms Identify and confirm prescribed medication vs. inconsistent reports•either due to the presence of non-prescribed medications or illicit drugs Add comments to reports as needed Document completed reports and items for further review Collaborate and communicate with other departments to maintain the highest quality standards for testing procedures If needed, assist with answering incoming phone calls to the Confirmation department from customers, including questions regarding basic toxicology, basic drug metabolism, assistance with report issues, and sending reports Complete internal and external rerun requests Final review of internal rerun requests Review calibration and quality control data for each batch of patient samples Perform data analysis on patient samples for multiple analytes using mass spec software programs Utilize established protocols to confirm retention time, precursor and product ions, and qualifier ions are within established ranges for peak qualification and note any discrepancies Identify patient samples requiring reinjections or re-extractions following established protocols Program reinjections to run on the mass spec instruments Document data analysis completed and items for further review Transmit completed data analysis to the Laboratory Information System (LIS) Assist in proficiency testing, monitoring of daily controls, and be responsible for operating within the established quality controls parameters; including the recognition of invalid data and bringing all errors to the supervisor's attention Complete updated reports as needed Ensure adherence to all regulatory requirements Other duties as assigned

Requirements:

PROFESSIONAL REQUIREMENTS

Regular and prompt attendance An advanced understanding of drug metabolism, toxicology, forensic testing, P450 enzymes, or testing principles specifically related to urine and oral fluid metabolism An advanced understanding of

LC-MS/MS

systems and data interpretation High level of attention to detail Proficient in operating complex laboratory instrumentation and computers with scientific software Ability to participate in method development, validation or research with Technical Supervision preferred Able and willing to follow established protocols employing acceptable forensic standards of analysis and the use of judgment in searching for solutions or new applications within one's own experience Must be able to work with limited supervision where the work assignments are subject to established procedures, practices, precedents, methods, techniques, standards, and/or well-defined policies Must be able to achieve superior results when work is reviewed in terms of quality, volume, timeliness, and adherence to established methods, standards and policies Participate in ongoing training and continuing education courses related to drug metabolism, toxicology, and

LC-MS/MS

systems Responsible for promoting a collaborative and entrepreneurial environment Must be able and willing to wear personal protective equipment (PPE) when required Proficient with Microsoft Office applications

EDUCATION AND EXPERIENCE REQUIREMENTS

Bachelor of Science in Chemistry, Pharmacology, Toxicology, Biology, or similar analytical science field with at least 2 years of

LC-MS/MS

data analysis experience Must have experience with toxicology (drug testing) chromatographic data analysis for patient specimens Must have experience with toxicology (drug testing) certifying for patient lab reports Preference for candidates with familiarity with

LC-MS/MS

instruments (other experience in instrumental analysis of HPLC or

LC-MS/MS

of drugs in biological tissues may be acceptable) Preference for candidates with familiarity with Agilent MS and LC systems•specifically MassHunter Acquisition and Quantitation programs Previous work with bodily fluids•such as urine and oral fluid is preferred

KNOWLEDGE, SKILLS AND ABILITIES

Ability to communicate effectively, orally and in writing Ability to coordinate laboratory functions and represent the toxicology laboratory professionally Excellent time management, documentation, and organizational skills Demonstrated troubleshooting abilities Must be flexible, innovative, and self-motivated Ability to plan and organize his/her work Ability to function independently and in a team environment Ability to listen, learn, and promote accountability and responsibility related to all processes

PHYSICAL REQUIREMENTS

Position requires sitting, walking, reaching, bending, stooping, and handling objects with hands and/or fingers, talking and/or hearing, and seeing

DIRECT REPORTS

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