Sr. Director, Operations and R&D Finance

At 10x Genomics, we are building the tools and services to master biology and advance human health. To fuel this mission, we need world-class financial leadership. We are looking for a leader who can be the primary business partner and financial architect for our global Operations and R D organizations. You will drive the financial strategy across the entire product lifecycle: allocation of investment for new products and services, guiding our sourcing and manufacturing scale-up, and continuously improving COGS for on-market products. This includes managing $450M+ of annual spend spanning COGS, R D, and capital expenditures. We expect you to be deeply immersed in the business; you will spend time on the manufacturing floor and in the labs with business partners, understanding the physical reality of our products to ensure every dollar spent drives both breakthrough innovation and sustaining cash flows. ### What You Will Be Doing

Strategic Partnership:

Serve as the primary financial partner to the President & Chief Scientific Officer, Chief Technology Officer, and Chief of Global Operations.

Gross Margin:

Own the end-to-end standard costing process and drive margin expansion through rigorous COGS and yield optimization across NPIs and on-market products. Bridge GAAP reporting (inventory reserves, warranty, absorption, etc) with plain-English insights and actionable analytics.

Operations & Supply Chain Planning:

Lead production planning, capex forecasting, and global supply chain partnerships. Develop and improve core operational analytics to guide rapid, data-driven decisions.

R D Investment & LRP:

Support pipeline investment decisions and Long-Range Planning (LRP) with robust financial frameworks. Evaluate platform-level ROI, capital allocation, and facilitate financial trade-off decisions from early-stage investment to commercial scale.

Team Leadership:

Build and develop a world-class FP&A team; elevate the function by recruiting top analytical talent.

Operational Scaling:

Design and implement lean workflows and automated systems across the company to ensure the organization can support rapid growth without linear headcount expansion. ### To Be Successful, You Will Need

• 12+ years of progressive finance experience, with at least 5 years in a senior leadership role.
• Deep cost accounting expertise in a manufacturing environment producing physical products
• Experience managing $300M+ budgets spanning COGS, R D, inventory, and capital expenditures across global sites.
• Strong command of US GAAP as it applies to manufacturing: standard costing, absorption, revenue recognition (ASC 606), inventory reserves, and warranty accounting.
• Proven team builder who has hired, developed, and retained high-caliber analytical talent.
• First-principles thinker who questions assumptions rather than defaulting to industry convention. Comfortable with ambiguity and able to structure problems from scratch.
• Exceptional communicator who can make complex financial and cost accounting concepts intuitive for non-financial audiences, including scientists, engineers, and executive leadership.
• Promote transparency and visibility: ensure data, goals, and rationale are clear and accessible to build trust and accountability across all functions.
• Expert-level financial modeling skills, including complex scenario and sensitivity analysis, and proficiency in building scalable models in Excel.
• Bachelor's degree in Finance, Accounting, Economics, or a quantitative field. #### Preferred Qualifications
• MBA or graduate degree in a quantitative discipline. A background or genuine interest in life sciences.
• Experience with ERP systems (Oracle preferred) and fluency in how financial systems connect to manufacturing execution systems.
• Data analytics skills and experience (Tableau, Power Pivot, Power Query, SQL, R, Python, etc.

). Below is the base pay range for this full-time position. The actual base pay will depend on several factors unique to each candidate, including one's skills, qualifications, and experience. At 10x, base pay is also just one component of the Company's total compensation package. This role is also eligible for 10x's equity grants, its comprehensive health and retirement benefit programs, and its annual bonus program or sales incentive program. During the hiring process, your 10x recruiter can share more about the Company's total compensation package. Pay Range $265,600--$359,400 USD About 10x Genomics At 10x Genomics, accelerating our understanding of biology is more than a mission for us. It is a commitment. This is the century of biology, and the breakthroughs we make now have the potential to change the world. We enable scientists to advance their research, allowing them to address scientific questions they did not even know they could ask. Our tools have enabled fundamental discoveries across biology including cancer, immunology, and neuroscience. Our teams are empowered and encouraged to follow their passions, pursue new ideas, and perform at their best in an inclusive and dynamic environment. We know that behind every scientific breakthrough, there is a deep infrastructure of talented people driving the life sciences industry and making it possible for scientists and clinicians to make new strides. We are dedicated to finding the very best person for every aspect of our work because the innovations and discoveries that we enable together will lead to better technologies, better treatments, and a better future. Find out how you can make a 10x difference. Individuals seeking employment at 10x Genomics are considered without regards to race, color, religion, national origin, age, sex, marital status, ancestry, physical or mental disability, veteran status, gender identity, or sexual orientation, or any other characteristic protected by applicable law. 10x does not accept unsolicited applicants submitted by third-party recruiters or agencies. Any resume or application submitted to 10x without a vendor agreement in place will be considered unsolicited and property of 10x, and 10x will not pay a placement fee. Please be aware of recruitment scams impersonating 10x Genomics. All recruiting communication will come from email addresses @10xgenomics.com. We also want to encourage you to apply to 10x Genomics positions directly on our careers site, Careers.10xgenomics.com or from reputable third party sites, such as LinkedIn or Indeed. We will never request payment or sensitive personal information during the recruiting process.