Associate Director, Demand & Revenue Forecasting Alnylam Pharmaceuticals $162,400-$219,600 paid time off United States, Massachusetts, Cambridge Sep 15, 2026 Overview We are seeking an experienced Associate Director to lead Demand and Revenue Forecasting for our US TTR Franchise. This key leadership role will be responsible for developing and overseeing comprehensive forecasting models and strategies. The ideal candidate will have a deep understanding of the biotech industry, strong analytical skills, and the ability to translate complex data into actionable insights to drive brand performance. This position will behybrid and primarily based in Cambridge, MA. Responsibilities Advanced forecasting experience, including developing different types of models (patient flow-based, unit trend-based (weekly/monthly) leveraging primary and secondary data sources

Develop robust forecasting assumptions related to market dynamics, competitive landscape, pricing, payer access, treatment algorithms, and patient flow

Monitor market dynamics, competitor performance, treatment paradigms, payer trends, and regulatory developments impacting forecast performance

Drive forecasting innovation through advanced analytics, predictive modeling, and automation tools

Collaborate with cross-functional teams including marketing, sales, market access, advanced analytics, and supply chain to ensure alignment and accuracy of forecasts

Proven track record presenting insights to senior executives and cross-functional leadership teams Qualifications Bachelor's degree in Engineering, Economics, Statistics, Mathematics, or a related field. MBA, MS, PhD, or other advanced degrees preferred.

8-10+ years of pharmaceutical or biotechnology forecasting experience.

Demonstrated experience in specialty, oncology, or other complex therapeutic areas.

Experience supporting product launch forecasting

Experience using IQVIA, Symphony, MMIT, or similar industry data sources.

Familiarity with data visualization and analytics platforms such as Power BI, Tableau, SQL, or R preferred About Alnylam We are the leader in RNAi therapeutics- a revolutionaryapproach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possibleand are just at the beginning of what's possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, wherean authentic, inclusive culture and breakthrough thinkingfuel one another. At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer. Before applying, please review Alnylam's CandidatePrivacy Notice regarding how Alnylam handles Personal Data you provide with your application for employment. #LI-MH1 #LI-Hybrid The pay range below reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity). Alnylam's robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together. Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website:https://www.alnylam.com/careers U.S. Pay Range

$162,400 — $219,600 USD