Scientist/ Senior Scientist, Product Development Employer Spiral Therapeutics Location South San Francisco, California (on-site) Salary competitive salary and benefits Start date Aug 19, 2026 View more categories View less categories Discipline Science/R D , Biotechnology , Biotherapeutics , CMC Required Education Doctorate/PHD/MD Position Type Full time Apply now Save job Click to add the job to your shortlist You need to sign in or create an account to save a job. Send job

Job Details Position Objectives:

Lead formulation development work at Spiral to support new products, including pre-formulation activities, formulation development and analytical testing. Design and evaluate new delivery platforms for local delivery in the ear, with the focus on long-lasting gel formulations. Develop drug product manufacturing processes, support CMOs in manufacturing and testing of drug products for clinical development programs. As a key member of a small and growing team, this individual will directly impact a wide range of activities along the product development pathway and will collaborate directly with colleagues across multiple functions.

Essential Functions:

Lead pre-formulation, formulation development for new drug candidates (small molecules, peptides and proteins) Design, evaluate and characterize new delivery platforms for local delivery in the ear Lead analytical testing of new formulation including selection of appropriate testing strategy, method development and development of product specifications as needed. Develop preclinical formulations and manufacturing processes for new drug products Support CMOs in manufacturing and testing of new products for clinical programs. Oversee detailed technical requirements, resource requirements, timelines and decision points of CMC activities for the new programs Prepare and/or oversee the preparation of the CMC section(s) of regulatory submissions

Education :

Ph.D. in Analytical Chemistry, Chemical Engineering, Materials Science, Pharmaceutical Sciences or a related discipline, or an equivalent level of knowledge and experience.

Experience :

3-8 years of experience in formulation development and drug product manufacturing In-depth scientific knowledge and hands-on experience in formulation development is required. Experience in extended-release local delivery systems is highly desirable Knowledge of analytical testing requirements for specific types of products is a must. Experience in analytical method development is desired Knowledge of GMPs and regulatory requirements as related to formulation development and drug product manufacturing is preferred. Experience with protein formulation and/or controlled delivery/ sustained release systems is preferred. Previous supervisory experience is a plus. Share this job Facebook Twitter LinkedIn Apply now Send job Apply now Save job Click to add the job to your shortlist You need to sign in or create an account to save a job. Get job alerts Create a job alert and receive personalized job recommendations straight to your inbox. Create alert Similar jobs Director/Sr. Director - Medicinal Chemistry (synthetic macrocycles) San Francisco, California Scientist II, Degrader Antibody Conjugate Characterization Brisbane, CA Associate Director Translational Pharmacokinetics and Pharmacokinetic/Pharmacodynamic Tarrytown, New York