Associate Director

• Protein Sciences EPM Scientific
• 3.3 Menlo Park, CA Job Details $200,000
• $250,000 a year 10 hours ago Qualifications Handling antibodies Investigational new drug (IND) applications Chemistry, manufacturing & controls Full Job Description Company Overview Our client is a stealth-mode biotechnology company developing next-generation antibody and protein therapeutics.

With research teams in both the U.S. and China, the company is advancing multiple programs toward IND-enabling studies and is seeking a key scientific hire to help build its development organization from the ground up. Position Summary This individual will serve as a technical leader supporting antibody characterization, develop-ability assessment, protein sciences, and early CMC activities. The role combines hands-on scientific work, CRO/CDMO management, and IND-enabling development efforts. The position will work closely with the CSO and have the opportunity to help build and lead a team as the company grows. Key Responsibilities Lead characterization and develop-ability assessments of monoclonal antibodies, bispecific antibodies, multispecific antibodies, and other protein therapeutics. Perform protein expression and purification using mammalian expression systems (HEK293, Expi293, or similar). Execute and interpret analytical and biophysical studies including SEC-HPLC, CE-SDS, DLS, HIC, IEX, icIEF, DSF, nanoDSF, and DSC. Assess aggregation, stability, charge variants, fragmentation, solubility, and other critical quality attributes. Design and execute formulation and forced degradation studies. Troubleshoot develop ability challenges including low expression, aggregation, poor stability, and manufacturing liabilities. Integrate analytical, biophysical, and functional data to support candidate selection. Manage CROs, CDMOs, and analytical partners, including timelines, budgets, and deliverables. Support process development, tech transfer, analytical development, and manufacturing readiness activities. Contribute to pre-IND and IND CMC strategy, including Module 3 documentation. Collaborate closely with scientific teams in both the U.S. and China. Participate in frequent cross-functional meetings and occasional travel. Qualifications PhD preferred (MS/BS considered with relevant experience) in Protein Chemistry, Biochemistry, Biophysics, Pharmaceutical Sciences, Molecular Biology, or related field. 5+ years (Senior Scientist), 8+ years (Associate Director), or 10+ years (Director) of industry experience. Strong experience with therapeutic antibodies and protein biologics. Experience with antibody characterization and develop ability assessments. Familiarity with bispecific, multispecific, or engineered antibody formats preferred. Experience supporting IND-enabling development and early CMC activities. Track record managing CROs and/or CDMOs. Comfortable working in a fast-paced startup environment. Authorization to work in the U.S. without sponsorship. Preferred Qualifications IND submission or Module 3 experience. Autoimmune or immunology therapeutic experience. Mandarin language proficiency. Experience working with teams in China. Startup or early-stage biotech experience. What They're Looking For Must-Have Antibody/protein therapeutics experience Protein characterization & develop-ability expertise Early CMC or IND-support experience

CRO/CDMO

management Onsite in Menlo Park Nice-to-Have Mandarin speaking Bispecific/multispecific antibody experience If this sounds like you please don't hesitate to apply in, we are actively reviewing resumes!