At Lilly, the work is demanding because patients are waiting. We unite caring with discovery to help make life better for people around the world, knowing that every decision, every detail, and every day matters. Headquartered in Indianapolis, Indiana, our over 50,000 employees around the globe take on complex challenges to discover and deliver life-changing medicines, strengthen how health is understood and managed, and support the communities we serve. This is hard, urgent, selfless work—but it's work worth doing. If you're driven by purpose and ready to bring your best to work that truly matters for patients, we invite you to join us. Orna Therapeutics, Inc., a wholly owned subsidiary of Eli Lilly and company is a biotechnology company pioneering innovative treatments for diseases that current therapies cannot effectively address. Employing groundbreaking circular RNA (circRNA) technology, along with proprietary lipid nanoparticles designed to selectively target T cells, Orna is advancing a new generation of RNA-based therapeutics. The company is focused on developing best-in-class treatments for autoimmune and oncology indications, including systemic lupus erythematosus, B-cell lymphoma, and multiple myeloma. We are looking for a motivated Senior scientist to join the bioanalysis team and support nonclinical studies for the company's diverse programs. Role is 100% lab-based work. The individual will actively take part in developing ligand binding assay (LBA) and PCR assays in guidance with scientists, perform sample testing and present results in team meetings. In this role you would have the opportunity to work with vibrant multi-disciplinary teams. What You'll Do Tissue processing from mice, rat and NHP invivo studies for RNA and protein extraction. Independently implement LBA and qPCR to measure large molecules such as protein and RNA from plasma and tissues samples. Perform method development and trouble shooting on LBA and qPCR-based assay with guidance. Provide high quality bioanalytical support with a focus on quantifications for

PK, TK, PD

assessment Deliver and present the experimental results to pre-clinical team Maintain detailed experimental protocols, electronic laboratory notebook Basic Qualifications BS with 0-4+ years of related industrial or academia experience, or MS with 0-2+ years of related industrial or academia experience. Major in biology, chemistry, pharmaceutical science or related fields Qualified applicants must be authorized to work in the United States on a full-time basis. Lilly will not provide support for or sponsor work authorization or visas for this role, including but not limited to

F-1 CPT, F-1 OPT, F-1 STEM

OPT, J-1, H-1B, TN, O-1, E-3, H-1B1, or L-1. Additional Skills/Preferences Experience and knowledge in RT-QPCR, ddPCR, bDNA and Ligand binding assay Performing data analysis using excel and GraphPad prism. Experience with Ligand binding assays on Luminex and MSD platform Experience in tissue sample processing is a plus Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form (https://careers.lilly.com/us/en/workplace-accommodation) for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response. Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status. Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees.

Our current groups include:

Africa, Middle East, Central Asia (AMECA), Black Employees at Lilly (BE@Lilly), Chinese Culture Network (CCN), EnAble, Evolve, Lilly Indian Network (LIN), Organization of Latinx at Lilly (OLA), Pride (LGBTQ+ Allies), Veterans Leadership Network (VLN) and Women's Initiative for Leading at Lilly (WILL). Actual compensation will depend on a candidate's education, experience, skills, and geographic location. The anticipated wage for this position is $71,250 - $187,000 Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly's compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees. #WeAreLilly