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Duke Clinical Research Institute
Shared Resource Lab Manager
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What they do
A Clinical Laboratory Manager manages laboratory research and procedures for numerous fields such as health, industry, or other natural sciences. Commonly oversees R&D, diagnostic or treatment to allow patients to receive better health outcomes. Responsible for regulatory, health and safety operations during laboratory activities.
$118,284 / year median in North Carolina
+12% projected growth
Job Description
Shared Resource Lab Manager Duke Clinical Research Institute paid time off, tuition assistance United States, North Carolina, Durham Aug 25, 2026 This position is grant funded School of Medicine Established in 1930, Duke University School of Medicine is the youngest of the nation's top medical schools. Ranked sixth among medical schools in the nation, the School takes pride in being an inclusive community of outstanding learners, investigators, clinicians, and staff where interdisciplinary collaboration is embraced and great ideas accelerate translation of fundamental scientific discoveries to improve human health locally and around the globe. Composed of more than 2,600 faculty physicians and researchers, nearly 2,000 students, and more than 6,200 staff, the Duke University School of Medicine along with the Duke University School of Nursing, and Duke University Health System comprise Duke Health, a world-class academic medical center. The Health System encompasses Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Duke Health Integrated Practice, Duke Primary Care, Duke Home Care and Hospice, Duke Health and Wellness, and multiple affiliations. High-Containment Facility Manager Regional Biocontainment Laboratory (RBL) - Duke Human Vaccine Institute Be You.
Position Overview:
The Duke Human Vaccine Institute (DHVI) is a multidisciplinary research organization within the Duke University School of Medicine dedicated to advancing basic, translational, and clinical research aimed at developing innovative vaccines, therapeutics, and diagnostic tools for infectious diseases that affect global health. The Duke Regional Biocontainment Laboratory (RBL), a division of DHVI, provides secure Biosafety Level 3 (BSL-3) laboratory facilities and support services for infectious disease research conducted on both Duke's main research campus and its Research Triangle Park (RTP) campus.Minimum Requirements:
Bachelor's degree in biology, microbiology, virology, or related scientific field. 5 to 7 years of related experience. Ability to communicate clearly in oral and written form. Ability to work with information systems, automated and technical equipment, or an equivalent combination of relevant education and/or experience The successful applicant must be eligible for and willing to:- Work with hazardous biological agents handled at BSL-2 and BSL-3
- Work with small animals handled at ABSL-2 and ABSL-3
- Comply with vaccination requirements when necessary
- Successfully complete and maintain US Department of Justice screening for Select Agent registration
- Achieve external certification for independent work at BSL-3
Preferred Qualifications:
Strong background in biosafety, previous BSL-3 compliance monitoring, supply chain and logistics management, and facilities management- Biological safety credential (RBP, CBSP) preferred
- Proficient in technical writing and safety training development and delivery
- Excellent interpersonal skills and experience working with researchers with diverse backgrounds and experiences Be Bold.
Position Description:
Maintain efficient day-to-day operations of the assigned high containment laboratory facility including, but not limited to, training new users, compliance monitoring, coordinating research activities of multiple laboratories, resource scheduling and billing Train and instruct research staff that will be utilizing the RBL facility. This could include various Duke research laboratories needing to work within a BSL3 facility for safety. Direct day-to-day activities of staff, as well as the project management goals of the facility. Utilize effective project and resource management needed for successful operation and service. Interact with various PIs and research leaders. Train and instruct facility maintenance staff to support the BSL-3 facility. This could include staff needing to enter to fix leaks or address alarms within the facility. Directly supervise the DHVI Laboratory Safety Officer Manage BSL-3 facility access Source and maintain an inventory of required safety supplies and laboratory equipment to ensure full compliance with Standard Operating Procedures (SOPs) and meet end user research needs Ensure required safety checks and waste removal is fully compliant with relevant SOPs. Coordinate laboratory and equipment decontamination and maintenance with relevant Duke offices/departments (e.g. Engineering and Operations) Participate in meetings of the Facility Operations and Core support teams. Participate in cost model development, use projections and budgeting for compliant cost recovery Participate as a member of the Duke Select Agent Team, along with the RBL Director and the RBL Operations Director. Participate in training personnel who conduct Select Agent research to assure compliance with the Select Agent Final Rule, and with all written Select Agent Plans (Incident Response, Safety, and Security). Participate in Select Agent drills and tabletop exercises- Coordinate incoming/outgoing material transfers with the facility leadership, the Duke Biological Safety Officer/Responsible Official and the Duke Office of Export Controls to ensure full compliance with all local, state and federal regulations Help coordinate proper maintenance and testing of critical containment equipment, and document annual BSL3 re-verification efforts Help coordinate proper emergency response procedures for the BSL-3 facility; may include responding onsite after hours Work to improve/optimize existing SOPs Develop and implement new SOPs; Lead development, optimization, qualification and validation efforts for assays and procedures, as requested by the research sponsor / Facility Director Successfully complete the High Containment Special Pathogens Health Review and be cleared by Duke's Employee Occupational Health and Wellness for work at BSL-3.