• Independently conduct activities including experiment design, planning, and execution; report processing, interpretation, review, and documentation of experimental results
• Contribute to studies that evaluate and rank lead T cell engager proteins for their biological effectiveness, focusing on key parameters such as potency, safety, and specificity.
• Propose, optimize, and integrate existing and new technologies and assays to deliver improved assay workflow and readouts.
• Culture and maintain primary human T cells, healthy cells, and multiple tumor cell lines. Integrate diverse cell populations into functional assays that support R D.
• Design, develop and optimize automated workflows to support high-throughput cell-based assays and molecular biology workflows.
• Support IND-enabling studies, including assay development, data generation, and documentation aligned with regulatory standards to advance therapeutic candidates through early development stages.
• Program and operate laboratory automation platforms, including Hamilton Liquid handling robots and other high-throughput instruments.
• Educate and train end users on automated methods, ensuring seamless adaptation and scalability of workflows.
• Collaborate with scientists to evaluate assay requirements and translate them into scalable automation solutions tailored to their specific needs.
• Collaborate effectively within the Applied Immunology and Discovery Immunology teams as well as the Protein Engineering team to advance research initiatives and contribute to the development of novel immune therapeutics.
• Support general lab operations with reagent preparation, instrument maintenance, and adherence to lab safety procedures.
• Maintain and implement good laboratory practices, including accurate electronic laboratory notebook entries, instrument and reagent validation, and personnel safety precautions.
• Use strong verbal and written communication skills to share scientific and project updates with the inter-disciplinary research team.

REQUIREMENTS

Education:

U.S. Masters degree, or foreign equivalent, in Biology, Cell Biology, Molecular Biology, Biochemistry, or a related biological science field.

Experience:

Two years of experience as a Research Associate or similar laboratory-based role in the biotechnology or pharmaceutical industry. Experience must include two years with each of the following:

• Propagation and banking of tumor cell lines
• Flow cytometry using panels of >10 colors
• T cell functional assays
• Gene modification approaches including nucleic acid transfection techniques
• Dendritic cell and T cell co-culture for the expansion of antigen-reactive sub-populations
• Cytokine release assays
• Programming, operating, troubleshooting, and maintaining automated liquid handling platforms
• Methods of T cell culture to drive reactivity, phenotype, and yield
• Mass spectrometry sample preparation

HOW TO APPLY

Send resume to . com with subject 951-REPR.