Process Chemist

Process Chemist at Discover International Process Chemist at Discover International in Los Angeles, California Posted in 9 days ago.

Type:

full-time

Job Description:

Process Chemist - Peptide / API Manufacturing LA County California (On-Site) $70/hour 6-Month Contract-to-Permanent Opportunity A leading peptide manufacturing organization is seeking a Process Development Scientist to support the advancement of innovative API processes from early development through full-scale cGMP manufacturing. This is a hands-on opportunity to work at the intersection of chemistry, process development, and commercial manufacturing supporting next-generation peptide and oligonucleotide medicines . The ideal candidate will bring strong synthetic chemistry expertise, process optimization experience, and the ability to collaborate cross-functionally in a fast-paced GMP manufacturing environment. Key Responsibilities Develop, optimize, and scale synthetic processes for peptide and oligonucleotide APIs from lab through manufacturing Support technology transfer activities from Process Development into Production across internal sites Monitor and optimize chemical reactions, purification operations, isolation, and drying processes Perform and interpret analytical testing including High-performance liquid chromatography purification, in-process sampling, and related process analytics Troubleshoot process, equipment, and manufacturing challenges to improve efficiency and yield Partner closely with Production, QA, QC, Engineering, and Supply Chain teams to ensure compliant execution Author and review batch records, protocols, reports, SOPs, and technical documentation Drive continuous improvement initiatives focused on safety, right-first-time execution, and scalable manufacturing readiness Qualifications PhD in Chemistry, Chemical Engineering, Organic Chemistry, or related discipline with 1+ year industry experience OR Master's degree with 5+ years relevant industry experience Minimum 4+ years of industry experience in organic chemistry, process chemistry, or API development Experience with peptide chemistry, peptide manufacturing, or complex molecule synthesis strongly preferred Strong understanding of synthetic route development, scale-up, and process optimization Familiarity with cGMP environments , deviation management, and technical documentation Hands-on experience with analytical techniques such as High-performance liquid chromatography, UPLC, and reaction monitoring tools preferred Excellent troubleshooting, communication, and independent problem-solving skills Preferred Experience Solid Phase Peptide Synthesis (SPPS) Oligonucleotide API manufacturing Tech transfer between R D and commercial manufacturing Purification, filtration, lyophilization, and drying operations Working in multi-site manufacturing environments Why Join Contract-to-hire opportunity with long-term growth potential Work with a recognized leader in peptide manufacturing Direct impact on therapies advancing modern medicine Strong exposure to development through commercial-scale production