Senior Director, Oncology Small Molecules and Targeted Delivery Pathology Therapeutic Area Lead, Clinical Pharmacology and Safety Sciences Position Available In Middlesex, Massachusetts

Introduction to role: Join our dedicated Research & Development team in Biopharmaceuticals R D as a Senior Director, Oncology Small Molecules and Targeted Delivery Pathology Therapeutic Area Lead. You will be accountable for the scientific output of Oncology small molecules (including PROTAC), Antibody Drug Conjugates and Radionuclides for the Global Pathology department, supporting discovery efficacy and safety across these modalities for AstraZeneca. You will be integral to developing and implementing pathology evaluations and strategies, incorporating new safety models, expanding multimodal analyses, supporting image analysis and artificial intelligence into the pathology workflows. This is your chance to make a meaningful impact on patients’ lives!

Accountabilities:

In this role, you will foster a culture of continuous improvement and scientific curiosity. You will collaborate with the pathology leadership team to integrate pathology findings with biomarker data, multimodal endpoints, nonclinical endpoints, and other relevant scientific information. You will demonstrate your extensive knowledge of toxicological pathology in support of drug discovery & development, and you will coach program pathologists. You will develop networks within the company to drive collaborative research and operational innovations. You will also build and influence networks across the pharmaceutical industry, including academic and industrial partners, competitors, and regulatory agencies.

Essential Skills/Experience:

DVM and international (ACVP/ECVP) board certification required. PhD in pathology, toxicology or related disciplines is a plus 10+ years of experience required in the toxicologic pathology area Significant experience in toxicologic pathology across drug modalities and therapy areas in support of drug development within the pharmaceutical industry Excellent communication skills and strong scientific track record with publications in high quality journals Broad cross-species toxicologic pathology expertise with experience of histopathological evaluation and/or peer review Strong familiarity with complementary data sets (e.g. clinical pathology, Investigative pathology endpoints) Highly effective written and communication skills with the ability to clearly convey complex pathology data to a wide range of stakeholders Demonstrated highly developed collaborative working and ability to lead within a matrix organization Ability to act as an external ambassador and to influence external organisations to enhance the image and reputation of AstraZeneca Previous managerial experience in pathology with proven ability to lead, mentor, motivate and develop others

In Office Requirement:

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That’s why we work, on average, a minimum of three days per week from the office. But that doesn’t mean we’re not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world. This role does not allow for remote or travel constructs. At AstraZeneca, we follow the science to explore and innovate. We are committed to making a difference by fusing data and technology with the latest scientific innovations to achieve the next wave of breakthroughs. We celebrate our successes and failures along the way, driven by our shared belief in what science can do. We are always learning from those living with diseases and harnessing digital, data science & AI to fast-forward our research. This is an environment where exploration and curiosity thrives. If your passion is science and you want to be part of a team that makes a bigger impact on patients’ lives, then there’s no better place to be. Ready to make a meaningful impact? Apply now! Date Posted 18-Jun-2025 Closing Date 10-Jul-2025Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form. AstraZeneca is a global, science-led, patient-focused biopharmaceutical company. We focus on discovering, developing and commercialising prescription medicines for some of the world’s most serious diseases. But we are more than one of the world’s leading pharmaceutical companies. At AstraZeneca, we’re dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science, challenge convention and unleash your entrepreneurial spirit. To embrace differences and take bold actions to drive the change needed to meet global healthcare and sustainability challenges. There is no better place to make a difference in medicine, patients, and society. An inclusive culture where you will connect different thinking to generate new and valuable opportunities. Where you will find a commitment to lifelong learning, growth and development for all. Our Inclusion & Diversity (I&D) mission is to create an inclusive and equitable environment where people belong, using the power of our diversity to push the boundaries of science to deliver life-changing medicines to patients. Inclusion and diversity are fundamental to the success of our company, because innovation requires breakthrough ideas that only come from a diverse workforce empowered to challenge conventional thinking. We’re curious about science and the advancement of knowledge. We find creative ways to approach new challenges. We’re driven to make the right choices and be accountable for our actions. As an organisation centred around what makes us human, we put a big focus on people. Across our business, we want colleagues to wake up excited about their day at the office, in the field, or in the lab. Along with our purpose to bring life-changing medicines to people across the globe, we have a promise to you: to help you realise the full breadth of your potential. Here, you’ll do work that has the potential to change your life and improve countless others. And, together with your team, you’ll shape a culture that unites and inspires us every day. This is your life at AstraZeneca.