Scientist III Position Available In Middlesex, Massachusetts

Advance the Future of Immune Cell Profiling in

Genetic Medicine Position:

Scientist –

In Vitro Immunology & Flow Cytometry Location:

Cambridge, MA|

Department:

Genetic Medicine / Immunology Are you passionate about cutting-edge immunology and drug discovery? We’re seeking a highly skilled and motivated Scientist to join our dynamic team focused on evaluating mRNA-LNP drug candidates using primary immune cell models and high-dimensional flow cytometry. This is a hands-on, lab-based role ideal for someone who thrives in a fast-paced, collaborative environment and is excited to contribute to the development of next-generation therapeutics. What You’ll Do Perform in vitro primary cell culture using human PBMCs, cynomolgus monkey PBMCs, and mouse splenocytes in 96-well plate formats. Conduct serial dilutions of drug candidates and apply treatments using multichannel pipettes. Execute flow cytometry assays including Live/Dead staining and antibody panels on BD FACS Canto II, Fortessa, and LSR II instruments. Analyze flow cytometry data using FlowJo to assess cell population shifts and phenotypic changes. Support mRNA-LNP screening efforts by evaluating immune responses and cellular uptake in primary immune cells. What You Bring M.S. in Immunology, Cell Biology, or a related field with 5-7 years of relevant experience, or Ph.D. with hands-on expertise in primary immune cell assays. Strong experience in flow cytometry, including panel design, staining, instrument operation, and data analysis. Proficiency in primary immune cell culture and handling of human and animal-derived cells. Experience with mRNA-LNP drug screening is highly desirable. Excellent organizational skills, attention to detail, and ability to work independently and collaboratively. If interested, please reach out directly to Lindsee Allienello at lallienello @ actalentservices.com.