SVP, US Medical Affairs Lead Position Available In Middlesex, Massachusetts

Job Description:

Company Overview:

Dyne Therapeutics is discovering and advancinginnovative life-transforming therapeutics for people living withgenetically driven neuromuscular diseases. Leveraging themodularity of its FORCE™ platform, Dyne is developing targetedtherapeutics that deliver to muscle and the central nervous system(CNS). Dyne has a broad pipeline for neuromuscular diseases,including clinical programs for myotonic dystrophy type 1 (DM1) andDuchenne muscular dystrophy (DMD) and preclinical programs forfacioscapulohumeral muscular dystrophy (FSHD) and Pompe disease.

Role Summary:

The Head of Medical Affairs, U.S. is the medicalleader responsible for the overall leadership & management of ourmedical affairs team in the U.S This role is a proactive strategicmedical partner within the clinical, and eventually the commercial,organization driving medical excellence and acting as a key memberof the Global Medical Affairs organization as the point person inU.S This role closely collaborates with the global medical affairsteam to build an aligned U.S. medical affairs structure andfacilitate the execution of the consolidated Global Medicalstrategic & tactical plan. In addition, this role ensures accurate,robust, and appropriate medical/scientific exchange of knowledgeand clinical expertise with internal stakeholders across the U.S.,and partners with relevant external stakeholders in driving successfor preparing the launch. This role is based in U.S. at theheadquarters in Waltham, MA.

Primary Responsibilities Include:

Works cross-functionally and especially closely with Global MedicalAffairs, Clinical Development/Operations, and Commercial as well asto develop and execute the strategic medical affairs plans. Buildand lead Field Medical Organization that faces Health CareProviders (HCPs) and U.S. Payers Maintains in-depth understandingof the Diseases state, product, competitors, marketplace, andrelated medical areas – included study design pre and post Buildand lead an efficient and agile Medical Affairs strategy team tooptimize the effectiveness of the strategy across this key market.

Collaborate and partner effectively with internalstakeholders/business partners, both global and regional teams.

Involvement in the scientific and medical communication strategyand in any non- promotional material review as per procedure. Oncethe MA is granted, responsible for the scientific review of anypromotional material. Deliver timely, fair balanced, objective,scientific and economic information, and education to health carecustomers and to internal business partners as required by businessLead the strategy and key tactics for U.S. medical affairs,including but not limited to KOL and Payer advisory boards,symposia, conferences, real-world data collection, payerengagements, etc Support diseases related Investigator InitiatedStudies (IIS) originating from the US through review, submission,evaluation, and recommendation of concepts/ proposals via thecompany process. Provide medical input into the disease models,market research lead by the Commercial and Market Access team. Planand lead U.S. RWD, epidemiological, and /or observational studiesto reinforce any evidence that can support regulatory and payerauthorities. Oversee the medical component of the lifecycle Leadand implement a high level of medical integrity and health careShape and optimize treatment paradigms, in collaboration withexternal and internal Think strategically to translatemedical/clinical insights of treatment paradigms into growthopportunities, process improvement and driving competitiveadvantage. Keen ability to make practical, realistic, fact-based,thoughtful, and timely decisions while building a collaborativeculture. Stimulate and motivate people and teams to develop andexecute medical excellence and medical leadership. Patient centricthinking, putting patient needs central in developing strategies todifferentiate the value we bring to customers. Identifyopportunities and take action to build strong scientifically basedrelationships; able to gather and represent professional views,partners with customers and internal Define ambitious goals andestablish priorities with clear responsibilities to ensure results;manages projects, activities and resources effectively.

Educationand Skills Requirements:

MD, PhD, Pharm D or other relevantterminal Ideally has Neuromuscular Disease experience, and shouldhave Rare Disease Diverse background of professional experienceincluding ten plus (10) years of Medical Affairs experience plusclinical development/operations knowledge, with in depth knowledgeof rare disease drug development, market access, commercialization,and life cycle management. Experience working with teams /individuals with varied cultural backgrounds and learning styles.

Intermediate to advanced competency and experience with a varietyapplications, including Microsoft Suite, MS Project, SharePointand/or other related project management tools. Strong interpersonalskills with the need to work closely with both external andinternal business partners. Willingness/ability to travel up to30-50% in the S. region and internationally at times. Fluent inEnglish (required) Excellent team player, strong decision maker,and ability to work in a matrix Ability to work independently as ahands-on manager, and proactively contribute as a resource whennecessary. Flexibility to adapt and meet the changing/growing needsof our customers High level of integrity, compliance, ethics, andtransparency The statements contained herein reflect generaldetails as necessary to describe the principles functions for thisjob, the level of knowledge and skill typically required, and thescope of responsibility, but should not be considered anall-inclusive listing of work requirements. Individuals may performother duties as assigned, including work in other functional areasto cover absences or relief, to equalize peak work periods orotherwise balance workload. This description is not intended to beconstructed as an exhaustive list of duties, responsibilities, orrequirements for the position. This position may change or assumeadditional duties at any time. The employee may be requested toperform different or additional duties as assigned. All Employeesare expected to adhere to all company policies and act as a rolemodel for company values. Dyne Therapeutics is an equal opportunityemployer and will not discriminate against any employee orapplicant on the basis of age, color, disability, gender, nationalorigin, race, religion, sexual orientation, veteran status, or anyclassification protected by federal, state, or local law.