Associate Scientist Position Available In Suffolk, Massachusetts

Associate Scientist Spectraforce Technologies United States, Massachusetts, Boston Jun 23, 2025

Position Title:

Associate Scientist Work Location:

Boston, MA 02115

Assignment Duration:

12 months

Position Summary:

This is an exciting opportunity in the Biochemistry and Biophysics Group within the Department of Pharmacology at our organization.

Key Responsibilities:

Develop and/or run quantitative biochemical and biophysical assays to support identification, characterization, and optimization of small molecule ligands from high throughput screening campaigns and medicinal chemistry efforts.
Conduct biochemical and biophysical studies to elucidate the modes of ligand interaction and mechanisms of action on target proteins.

Qualification & Experience:

BS/BA degree in biochemistry, biophysics or a related discipline with a minimum of 1-5 years industry experience; or a MS degree in biochemistry, biophysics or a related discipline with 1 or more years of industry experience, preferably with a focus on assay development and compound profiling within a drug discovery environment.
Candidate should have basic knowledge of biochemistry, biophysics and molecular biology.
Candidate should have prior experience with basic biochemical and/or biophysical techniques.
Candidate should be highly motivated, driven, and willing to take the initiative to learn new scientific methodologies.
Candidate should be a strong team player.
Candidate should have excellent oral and written communication skills.
Candidate should be comfortable using a PC computer and proficient in Windows-based operating systems and basic applications, such as spreadsheets and databases.
Experience in the use of automated liquid handlers such as Echo, Bravo, Biomek, or Hamilton and data analysis and presentation software such as TIBCO Spotfire, Excel and PowerPoint.
Proven ability to independently design, develop and implement biochemical and biophysical screening assays using detection modalities such as: TR-FRET, FP, LC-MS, radiochemical, surface plasmon resonance (BIAcore), fluorescence-based thermal shift (TdF), and/or isothermal titration calorimetry (ITC).
Hands-on experience performing steady-state and transient-state kinetic experiments to study enzymes and inhibitors.
Direct experience in recombinant protein expression using bacteria, insect (baculovirus) and/or mammalian cell-based systems and purification using automated chromatographic separation systems.