Scientist III Position Available In Middlesex, Massachusetts

Scientist III#25-62808
Cambridge, MA

All On-site Job Description Position Overview:

Seeking a Contract Scientist to support the siRNA group within the Biotherapeutics and Genetic Medicine (BGM) department. This temporary position offers the opportunity to contribute to the design and execution of cutting-edge experimental approaches to address key scientific challenges related to oligonucleotide therapeutics. The successful candidate will apply their scientific expertise to drive innovation, collaborate across teams, and support the development of Client RNA-based therapies.

Responsibilities:

Lead research efforts within a cross-functional team to advance siRNA platform development for therapeutic applications.
Resolve key project hurdles and assumptions utilizing available information and technical expertise
Work autonomously to perform laboratory research or develop methods with minimal supervision, consistently delivering high-quality results.
Demonstrate expertise in a wide range of relevant technologies and methodologies.
Conceive and execute Client scientific research that achieves project goals
Maintain high productivity in the laboratory, ensuring efficiency in experiment execution.
Analyze and interpret multidisciplinary data, generating conclusions that drive future experimental directions.
Contribute to internal reports, presentations, and potentially intellectual property filings.

Skills and Requirements:

PhD (or equivalent experience) in Cell Biology, Molecular Biology, Biochemistry, or related field. Alternatively, a Master’s degree with 8 years of significant relevant experience may be considered.
Strong hands-on experience in cell and molecular biology, including mammalian cell culture, mRNA isolation/quantitation by qPCR, sequencing (NGS/Sanger), and protein quantification by ELISA and western blot.
Experience in oligonucleotide therapeutics is a plus.
Familiarity with CNS disease models and DNA/RNA editing tools is highly desired.
Outstanding aptitude for experimental design and execution, efficient assay development and creative problem solving.
Ability to thrive in a dynamic, fast-paced research environment.
Collaborative team player with excellent communication skills.