Molecular Biology Assay Developer Position Available In Suffolk, Massachusetts

Molecular Biology Assay Developer

AA2IT – 5.0

Boston, MA Job Details Full-time $44.50 an hour 17 hours ago Benefits Health insurance Dental insurance 401(k) Vision insurance Qualifications Microsoft PowerPoint Biochemistry Microsoft Excel Bachelor of Science Mid-level Windows Assay development Master’s degree Databases Bachelor’s degree Biochemistry Biophysics 1 year Communication skills Molecular biology

Full Job Description Qualifications:

Education Requirement:

BS/BA degree in biochemistry, biophysics or a related discipline with a minimum of 1-5 years industry experience; or a MS degree in biochemistry, biophysics or a related discipline with development and compound profiling within a drug discovery environment.

Required Skills:

Candidate should have basic knowledge of biochemistry, biophysics and molecular biology Candidate should have prior experience with basic biochemical and/or biophysical techniques Candidate should be highly motivated, driven, and willing to take the initiative to learn new scientific methodologies Candidate should be a strong team player Candidate should have excellent oral and written communication skills Candidate should be comfortable using a PC computer and proficient in Windows-based operating systems and basic applications, such as spreadsheets and databases Experience in the use of automated liquid handlers such as Echo, Bravo, Biomek, or Hamilton and data analysis and presentation software such as TIBCO Spotfire, Excel and PowerPoint.

Preferred Attributes:

Proven ability to independently design, develop and implement biochemical and biophysical screening assays using detection modalities such as: TR-FRET, FP, LC-MS, radiochemical, surface plasmon resonance (BIAcore), fluorescence-based thermal shift (TdF), and/or isothermal titration calorimetry (ITC). Hands-on experience performing steady-state and transient-state kinetic experiments to study enzymes and inhibitors. Direct experience in recombinant protein expression using bacteria, insect (baculovirus) and/or mammalian cell-based systems and purification using automated chromatographic separation systems.

Responsibilities:

This is an exciting opportunity in the Biochemistry and Biophysics Group within the Department of Pharmacology at MRL-Boston. The successful candidate is expected to: Develop and/or run quantitative biochemical and biophysical assays to support identification, characterization, and optimization of small molecule ligands from high throughput screening campaigns and medicinal chemistry efforts. Conduct biochemical and biophysical studies to elucidate the modes of ligand interaction and mechanisms of action on target proteins.

Job Type:

Full-time Pay:

$44.50 per hour

Benefits:

401(k) Dental insurance Health insurance Vision insurance

Schedule:

8 hour shift Application Question(s): Q1: How many years of experience performing steady-state and transient-state kinetic experiments to study enzymes and inhibitors. Q2: How many years of experience in recombinant protein expression using bacteria, insect (baculovirus) and/or mammalian cell-based systems and purification using automated chromatographic separation systems. Q3: How many years of exp in automated liquid handlers such as Echo, Bravo, Biomek, or Hamilton Q4: How far you live and how will you commute to 33

Avenue Louis Pasteur, Boston, MA Experience:

recombinant protein expression: 3 years (Preferred) automated liquid handlers: 3 years (Preferred)

Work Location:

In person