Scientist, Immunology Position Available In Middlesex, Massachusetts

Job Title:

Scientist, Immunology Location:

Waltham, MA About the Job We are seeking a highly motivated and skilled immunologist to join the Preclinical immunology team within the mRNA Center for Excellence to support the advancement of mRNA vaccine/therapeutics platform. As an experienced immunologist you will be leading from the bench by planning, developing and executing in vitro immunological assays. You will design in vivo studies and analyze tissue samples to determine the immune response in various disease models upon treatment with mRNA vaccines. We are an innovative global healthcare company that helps the world stay ahead of infectious diseases by delivering more than 500 million vaccine doses a year. Across different countries, our talented teams are exploring new technologies to protect people and promote healthy communities. We chase the miracles of science every single day, pursuing progress to make a real impact on millions of patients around the world.

Main Responsibilities:

Evaluate the innate and adaptive immune responses elicited by various mRNA vaccine candidate using immunological assay to determine the Immunogenicity and reactogenicity. Develop in vitro assays using human/mouse primary immune cells or co-culture models to understand the mRNA-LNPs uptake and downstream readouts using flow cytometry Develop in vitro models using various human immune cells to test lead mRNA-LNP candidates and assess downstream read-outs such as, cytokine secretion and phenotyping of immune cell in response to treatment Utilize techniques such as Flow cytometry, ELISA, Luminex to generate high-quality data to support the mRNA platform Maintain cell cultures, perform transfection on various human immune and determine protein expression as well as measuring various immune parameters by Flow cytometry to understand the immunological mechanism of mRNA LNP vaccine candidate Design in vivo studies to test mRNA-LNPs and perform analysis on multiple cells obtained from different tissues to assess immune cell response and its mechanism in relevant disease models Manage CRO for In vivo mouse studies Train and mentor other members of the team Conduct decision-quality research, organize, analyze and interpret data, summarize results and prepare technical reports. Prepare scientific presentations and report project progress at internal team meetings and scientific research forums About You Earned Ph.D. in immunology or similar scientific field required, ideally with some experience in a research laboratory or pharma/ biotech company setting (0-3 years) Strong background in immunology with extensive hands-on experience in Flow cytometry, ELISA, human cell culture is essential Experience measuring cytokines using Luminex and ELISA technology is needed Excellent communication skills, both oral and written with the ability to convey complex scientific concepts to key internal and external stakeholders Motivation to learn new techniques with strong problem-solving skills and a proactive approach to research challenges Well organized, with a curious mindset and extreme attention to detail. Strong desire to make an impact Ability to work collaboratively in a fast-paced, cross-functional, demanding work environment without compromising quality. Understanding of project timelines and able to adjust priorities as needed Why Choose Us? Bring the miracles of science to life alongside a supportive, future-focused team. Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally. Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact. Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave. Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law. #GD-SP #LI-SP #LI-Onsite #vhd Pursue progress, discover extraordinary Better is out there. Better medications, better outcomes, better science. But progress doesn’t happen without people – people from different backgrounds, in different locations, doing different roles, all united by one thing: a desire to make miracles happen. So, let’s be those people. At Sanofi, we provide equal opportunities to all regardless of race, colour, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, ability or gender identity. Watch our ALL IN video and check out our Diversity Equity and Inclusion actions at sanofi.com! US and Puerto Rico Residents Only Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally inclusive and diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; natural or protective hairstyles; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law. North America Applicants Only The salary range for this position is: $84,000.00 – $121,333.33 All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs. Additional benefits information can be found through the LINK. Global Terms & Conditions and Data Privacy Statement Sanofi is dedicated to supporting people through their health challenges. We are a global biopharmaceutical company focused on human health. We prevent illness with vaccines, provide innovative treatments to fight pain and ease suffering. We stand by the few who suffer from rare diseases and the millions with long-term chronic conditions. With more than 100,000 people in 100 countries, Sanofi is transforming scientific innovation into healthcare solutions around the globe. Discover more about us visiting www.sanofi.com or via our movie We are Sanofi As an organization, we change the practice of medicine; reinvent the way we work; and enable people to be their best versions in career and life. We are constantly moving and growing, making sure our people grow with us. Our working environment helps us build a dynamic and inclusive workplace operating on trust and respect and allows employees to live the life they want to live. All in for Diversity, Equity and Inclusion at Sanofi – YouTube