? High Salary: Principal Scientist Quantitative Systems Position Available In Middlesex, Massachusetts
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Job Description
Job Description:
Job Title:
Principal Scientist Quantitative Systems Location:
Waltham, MA About the Job Are you ready to shape the future ofmedicine? The race is on to speed up drug discovery and developmentto find answers for patients and their families. Your skills couldbe critical in helping teams accelerate Progress. Join ourQuantitative Systems Pharmacology (QSP) group as a PrincipalScientist and you’ll support our R D portfolio with mechanisticdisease modeling. This position is based in Cambridge, MA. We arean innovative global healthcare company with one purpose: to chasethe miracles of science to improve people’s lives. We’re also acompany where you can flourish and grow your career, with countlessopportunities to explore, make connections with people, and stretchthe limits of what you thought was possible. Ready to get started?
Main Responsibilities:
- Function as part of a team to develop andapply multiscale computational models of complex diseases based ondetailed biological mechanistic knowledge to support model-informeddrug discovery & development.
- Survey literature to gainunderstanding of critical physiological processes to berepresented, and identify suitable mechanistic elements, data,parameters and assumptions to be included.
- Identify and analyzesuitable internal preclinical and clinical data to inform modelingactivities.
- Analyze simulation results and identify appropriatestrategies to resolve issues pertaining to model performance andaccuracy.
- Maintain extensive documentation of model developmentprocess, and data analysis.
- Maintain quantitative systemspharmacology expertise through comprehensive education
- undefined
- Communicate modeling predictions to key stakeholders. About You
- PhD with an excellent track record of productivity in the areasof systems pharmacology/biology, computational biology, biomedicalengineering or related field, as manifested by publications andscientific presentations in conferences
- At least 2 years ofPostdoctoral experience in disease modeling/QSP
- Experience indrug discovery/development a plus, especially in bioinformatics orpharmacometrics.
- Proficiency in mathematical modeling usingdifferential equations.
- Extensive experience in computationaltools such as MATLAB, Julia and R (MATLAB preferred).
- Excellentoral and written communication skills.
- Ability to quickly learnpathophysiology in indications of interest, and treatmentapproaches in immunology.
- Highly motivated, detail-oriented, andindependent researcher.
- Able to thrive in a collaborative,multi-disciplinary team environment.
- Strong commitment toon-the-job-training.
- undefined Preferred but no required:
Knowledge of Immunology Why Choose Us?
- Bring the miracles ofscience to life alongside a supportive, future-focused team.
- Discover endless opportunities to grow your talent and drive yourcareer, whether it’s through a promotion or lateral move, at homeor internationally.
- Enjoy a thoughtful, well-crafted rewardspackage that recognizes your contribution and amplifies yourimpact.
- Take good care of yourself and your family, with a widerange of health and wellbeing benefits including high-qualityhealthcare, prevention and wellness programs and at least 14 weeks’gender-neutral parental leave.
Sanofi Inc. and its U.S. affiliatesare Equal Opportunity and Affirmative Action employers committed toa culturally diverse workforce. All qualified applicants willreceive consideration for employment without regard to race; color;creed; religion; national origin; age; ancestry; nationality;marital, domestic partnership or civil union status; sex, gender,gender identity or expression; affectional or sexual orientation;disability; veteran or military status or liability for militarystatus; domestic violence victim status; atypical cellular or bloodtrait; genetic information (including the refusal to submit togenetic testing) or any other characteristic protected by law.
GD-SA LI-SA
LI-Onsite vhd All compensation will be determinedcommensurate with demonstrated experience. Employees may beeligible to participate in Company employee benefit programs, andadditional benefits information can be found here.